37619-38-8Relevant academic research and scientific papers
2-TOSYLOXYMETHYLCYCLANONES: RING SIZE DEPENDENCE OF FRAGMENTATION VERSUS INTRAMOLECULAR ALKYLATION
Heinz, Uwe,Adams, Elisabeth,Klintz, Ralf,Welzel, Peter
, p. 4217 - 4230 (2007/10/02)
The results reported seem to indicate, that in the presence of a nucleophilic base intramolecular alkylation is the normal reaction mode of tosyloxymethylcyclanones of type 14 and that the fragmentation reaction of five-membered compounds is the exception, probably because of the high steric energy of the alkylation transition states, e.g. of type E.
Oxidation of 1-hydroxyazetidines to four-membered cyclic nitrones and β-lactams
Elburg, P. A. van,Reinhoudt, D. N.
, p. 381 - 387 (2007/10/02)
The 1-(benzyloxy)azetidines 7a-c and 16a,b were synthesized by reductive cyclization of the corresponding oximes 5a-c and 14a-d.Oxidation of the 1-hydroxyazetidines 8a-c and 17 with PbO2 afforded the corresponding four-membered cyclic nitrones 18a-c and t
