37620-42-1Relevant academic research and scientific papers
Arylboronic Acid Catalyzed Dehydrative Mono-/Dialkylation Reactions of β-Ketoacids and Alcohols
Feng, Juhua,Hu, Haipeng,Ni, Hailiang,Qiu, Yuqian,Wang, Cuilin,Wang, Guangtu,Wang, Hanguang,Wang, Wei,Wu, Xin,Yue, Guizhou,Zou, Ping
supporting information, p. 832 - 836 (2022/02/05)
The dehydrative mono-/dialkylation reactions of alcohols and β-ketoacids were realized under arylboronic acid catalysis, furnishing a series of β-aryl ketones and β-ketoesters in yields of 15–99%, with CO2 and H2O being the byproduct
Photocatalytic decarboxylative coupling between α-oxocarboxylicacids and alkenes
Chen, Ziyue,Lu, Fangling,Yuan, Feng,Sun, Juanjuan,Du, Linyu,Li, Zhen,Gao, Meng,Shi, Renyi,Lei, Aiwen
, p. 1497 - 1500 (2019/11/16)
Photocatalytic decarboxylative cross-coupling which achieves the derivatization of widespread organic acids has become a hot topic in organic synthesis. As special acids, α-oxocarboxylicacids show the great potential in running decarboxylation to construc
A from the aromatic acid directly preparing aromatic ketone method (by machine translation)
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Paragraph 0126; 0127, (2019/01/06)
A process for preparing aryl ketone of the method, it is in order to aromatic carboxylic acid (ArCOOH) and olefin as raw materials, triphenylphosphine as a deoxidizing agent, under the irradiation of the blue lamp, in dichloromethane and water solution, under argon atmosphere, in the presence of a small amount of potassium phosphate, in order to [Ir (dF (CF3 ) Ppy)2 (Dtbbpy)] PF6 As the photocatalyst, get the aromatic compounds. The method easily available raw materials, mild reaction conditions, wide adaptability. (by machine translation)
An Atom-Economical Route to Substituted β-Arylethyl Ketones: Phosphomolybdic Acid-Catalyzed Carbohydroxylation of Terminal Alkynes in Organic Carbonate
Yang, Guo-Ping,Zhang, Nan,Ma, Nuan-Nuan,Yu, Bing,Hu, Chang-Wen
, p. 926 - 932 (2017/03/27)
A highly efficient and atom-economical route for the synthesis of substituted β-arylethyl ketones was developed by using cheap phosphomolybdic acid (H3PMo12O40) as catalyst and non-volatile propylene carbonate (PC) as green solvent via the carbohydroxylation of terminal alkynes with benzylic alcohols under mild conditions. Various functional groups on the benzylic alcohols and terminal alkynes were tolerated, giving the corresponding substituted β-arylethyl ketones as products in good to excellent yields (up to 95%). It is worth noting that a turnover number (TON) of up to 520 was achieved in the protocol. The mechanism investigation showed that PC might stabilize the heteropoly anion and the carbocation intermediate thus facilitating the carbohydroxylation reaction. (Figure presented.).
Synthesis of β,β-diaryl propiophenones via palladium-catalyzed domino arylboronation, elimination and enone hydroarylation of enaminones
Zhong, Shanshan,Lu, Yu,Zhang, Yan,Liu, Yunyun,Wan, Jie-Ping
supporting information, p. 6270 - 6273 (2016/07/11)
The syntheses of β,β-diaryl aryl propiophenones have been realized via palladium-catalyzed domino reactions of dimethyl amino functionalized enaminones and aryl boronic acids. This is the first example of transition metal-catalyzed enaminone C-N bond conversion for the generation of a new C-C(aryl) structure.
Synthesis of Substituted Aryl Ketones by Addition of Alcohols to Alkynes Using Amberlyst-15/Ionic Liquid as a Recyclable Catalytic System
Wagh, Kishor V.,Bhanage, Bhalchandra M.
supporting information, p. 759 - 764 (2015/03/30)
A highly efficient protocol for the synthesis of substituted aryl ketones by using Amberlyst-15 immobilized in [Bmim][PF6] ionic liquid has been firstly developed. The present protocol works under metal-free, solvent-free, mild reaction conditions with 100% atom efficiency. The various aryl ketones were obtained in good to excellent yields. The developed catalytic system was recycled efficiently up to five cycles without significant loss in catalytic activity.
Palladium-catalyzed conjugate addition of arylsulfonyl hydrazides to α,β-unsaturated ketones
Chen, Wen,Chen, Hui,Xiao, Fuhong,Deng, Guo-Jun
supporting information, p. 4295 - 4298 (2013/08/23)
A palladium-catalyzed desulfitative-denitrogenative conjugate addition of arylsulfonyl hydrazides to α,β-unsaturated ketones is described. The reaction showed very good selectivity and tolerated a wide range of functionalities under an atmosphere of oxygen with or without the aid of a metal co-oxidant. The Royal Society of Chemistry 2013.
Palladium-catalyzed desulfitative conjugate addition of aryl sulfinic acids and direct ESI-MS for mechanistic studies
Wang, Huifeng,Li, Yaming,Zhang, Rong,Jin, Kun,Zhao, Defeng,Duan, Chunying
supporting information; experimental part, p. 4849 - 4853 (2012/07/02)
A new and efficient method for palladium(II) catalytic desulfitative conjugate addition of arylsulfinic acids with α,β-unsaturated carbonyl compound has been developed. The key reacting intermediates including aryl Pd(II) sulfinic intermediate, aryl Pd(II), and C=O-Pd complexes were captured by ESI-MS/MS, which provide new experimental evidence for the understanding of addition mechanism.
Iron(III)-catalyzed addition of benzylic alcohols to aryl alkynes - A new synthesis of substituted aryl ketones
Jana, Umasish,Biswas, Srijit,Maiti, Sukhendu
experimental part, p. 5798 - 5804 (2009/06/08)
A new, efficient and direct addition of benzylic alcohols with terminal aryl alkynes was developed with the inexpensive, non-toxic, FeCl3 catalyst in nitromethane. The reaction provides a simple method for the synthesis of substituted aryl ketones under mild conditions, and the reaction is highly atom-economical. Several substituted terminal alkynes underwent smooth reaction with various substituted benzylic alcohols. The electron-rich alkynes reacted more efficiently and gave higher yields than did the neutral or electron-deficient alkynes. A wide range of functional groups were tolerated in the developed protocol. The intermediate of this reaction was isolated, and a possible mechanism has been proposed. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
