37632-18-1

Usage

Uses

Used in Pharmaceutical Industry:
4-Methoxyphenylphosphonic dichloride is used as an intermediate in the synthesis of various pharmaceuticals for its ability to form key chemical bonds and contribute to the development of new drugs.
Used in Agrochemical Industry:
4-Methoxyphenylphosphonic dichloride is used as an intermediate in the synthesis of agrochemicals to help create effective pesticides and other agricultural products that protect crops and enhance yields.
Used in Organic Compounds Synthesis:
4-Methoxyphenylphosphonic dichloride is used as a versatile intermediate in the synthesis of various organic compounds, enabling the creation of a wide range of chemical products for different industries.

InChI:InChI=1/C7H7Cl2O2P/c1-11-6-2-4-7(5-3-6)12(8,9)10/h2-5H,1H3

Upstream product

• 19909-85-4 dichloro-4-methoxyphenylphosphine 
• 100-66-3 methoxybenzene 
• 2097-72-5 bis(p-anisyl)mercury 
• 3762-33-2 diethyl (p-methoxyphenyl)phosphonate 
• 64955-93-7 tetrachloro-(4-methoxy-phenyl)-phosphorane 

Downstream Products

• 362477-44-9 (4-methoxy-phenyl)-phosphonic acid bis-(2-ethoxy-ethyl) ester 
• 362477-47-2 (4-methoxyphenyl)phosphonic acid bis(2,2,2-trifluoroethyl) ester 
• 21778-19-8 (4-methoxyphenyl)phosphonic acid 
• 100926-18-9 C₁₄H₁₆NO₃P 
• 362476-92-4 (3-benzyloxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-biphenyl-4-yl-ethyl ester 
• 362476-88-8 (3-benzyloxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid cyclohexylmethyl ester 
• 362477-04-1 (3-benzyloxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-diethylamino-ethyl ester 
• 362476-96-8 (3-benzyloxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-pyridin-2-yl-ethyl ester 
• 362476-87-7 (3-benzyloxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid hexyl ester 
• 1026438-73-2 (3-benzyloxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 3,3,3-trifluoro-propyl ester 
• 362476-90-2 (3-benzyloxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid phenethyl ester 
• 362476-89-9 ((R)-3-Benzyloxycarbamoyl-1,3,4,9-tetrahydro-β-carbolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid methyl ester 

Relevant academic research and scientific papers

N-hydroxylamines: Influence of Substituents on the Competitive Migration of Aryl and Phenyl Groups in the Lossen-like Rearrangement of their O-Methanesulphonyl Derivatives

The N-hydroxylamines ArPhP(O)NHOH (4) (Ar=p-XC6H4; X=MeO, Me, Cl, NO2) have been prepared from the corresponding phosphinic chlorides (3) using O-(trimethylsilyl)hydroxylamine and converted into the O-methanesulphonyl derivatives

SYNTHESIS OF PHOSPHONIC DICHLORIDES AND CORRELATION OF THEIR P-31 CHEMICAL SHIFTS

Various mono-substituted diethyl arylphosphonates were prepared in good yield by treatment of aryl bromides or iodides with triethyl phosphite in the presence of NiCl2 or alternatively, addition of the aryl grignard reagent to diethyl phosphorochloridate.