376353-72-9Relevant academic research and scientific papers
2-Ethyl and 2-ethylidene analogues of 1α,25-dihydroxy-19-norvitamin D3: Synthesis, conformational analysis, biological activities, and docking to the modeled rVDR ligand binding domain
Sicinski, Rafal R.,Rotkiewicz, Piotr,Kolinski, Andrzej,Sicinska, Wanda,Prahl, Jean M.,Smith, Connie M.,DeLuca, Hector F.
, p. 3366 - 3380 (2002)
Novel 19-nor analogues of 1α,25-dihydroxyvitamin D3 were prepared and substituted at C-2 with an ethylidene group. The synthetic pathway was via Wittig - Horner coupling of the corresponding A-ring phosphine oxides with the protected 25-hydroxy
