19910-33-9Relevant articles and documents
Visible Light-Driven Carboxylation of Olefins by Using 2D Metal-Free Covalent Organic Framework as Intrinsic Photocatalyst: A Sustainable Approach for CO2 Utilization
Das, Anjan,Ghosh, Swarbhanu,Manirul Islam, Sk.,Sarkar, Priyanka
, (2022/05/20)
Photocatalytic metal-free carboxylation of olefins offers an environment-friendly approach for resolving the increasing energy issue as well as mitigating the dilemma caused by the greenhouse effect. Carboxylation of styrene and its derivatives by photocatalytic CO2 reduction reaction shows great potential for sustainable utilization of greenhouse gas CO2 into valuable chemicals. Herein, we have constructed a highly crystalline and thermally stable 2D porous covalent organic framework (COF) having very low band-gap energy, 1.8 eV and it shows efficient photocatalytic activity towards the carboxylation of aryl-alkenes in good yields in presence of p-terphenyl as a co-catalyst at ambient temperature under visible light irradiation and 1 atmospheric CO2 pressure which facilitates to overcome the current transition metal catalyzed approaches. In addition, TR-OT COF is a proficient and highly selective catalyst with outstanding recyclability. This suggests that this COF material is a novel photocatalyst for CO2 reduction towards α, β-carboxylation of styrene and its derivatives under 20 W light-emitting diode (LED) light.
TYK2 INHIBITORS AND USES THEREOF
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Paragraph 0625; 0628; 0629, (2016/09/26)
The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
Direct amino acid-catalyzed cascade reductive alkylation of arylacetonitriles: High-yielding synthesis of ibuprofen analogs
Ramachary, Dhevalapally B.,Shiva Prasad
scheme or table, p. 5246 - 5251 (2010/11/03)
A novel approach for a one-pot, three-component reductive alkylation (TCRA) reaction of arylacetonitriles-containing electron-withdrawing groups with aldehydes/ketones and 1,4-dihydropyridine via iminium-catalysis has been developed. Many TCRA reaction products have direct applications in agricultural and pharmaceutical chemistry.