3769-51-5Relevant academic research and scientific papers
Microwave-assisted convenient synthesis of α,β-unsaturated esters and ketones via aldol-adduct elimination
Suman, Pathi,Nageswara Rao, Rayala,China Raju, Bhimapaka
, p. 1548 - 1559 (2013/09/02)
Various fluorinated 3-oxo ester/1,3-diketones were reacted with carbonyl compounds, in presence of piperidine and under microwave irradiation, to afford (E)-α,β-unsaturated esters and ketones in good yields. The systematic study reveals that the reaction proceeded through the formation of aldol adduct. The method provides a new and simple way for C,C bond formations. Copyright
Tandem mass spectrometry based investigation of cinnamylideneacetophenone derivatives: Valuable tool for the differentiation of positional isomers
Resende, Diana I. S. P.,Silva, Eduarda M. P.,Barros, Cristina,Domingues, M. Rosario M.,Silva, Artur M. S.,Cavaleiro, Jose A. S.
experimental part, p. 3185 - 3195 (2012/04/10)
Cinnamylideneacetophenones have been extensively used as versatile starting materials in numerous different transformations. The structural characterization of this type of compounds is, therefore, of crucial importance since it can give information on th
Amine-promoted synthesis of vinyl aziridines
Armstrong, Alan,Pullin, Robert D. C.,Jenner, Chloe R.,Scutt, James N.
supporting information; experimental part, p. 3499 - 3502 (2010/08/06)
N-Unsubstituted vinyl aziridines were synthesized via an amine-promoted regioselective nucleophilic aziridination of α,β,γ,δ- unsaturated carbonyl compounds. The reaction is completely regioselective (>95: 5) for the α,β-alkene and completely diastereosel
Epoxidation of (E,E)-cinnamylideneacetophenones with hydrogen peroxide and iodosylbenzene with salen-MnIII as the catalyst
Santos, Clementina M. M.,Silva, Artur M. S.,Cavaleiro, Jose A. S.,Levai, Albert,Patonay, Tamas
, p. 2877 - 2887 (2008/03/13)
(E,E)-Cinnamylideneacetophenones 3a-j were epoxidized under mild conditions with Jacobsen's catalyst 4 and hydrogen peroxide or iodosylbenzene as oxidants. γ,δ-Monoepoxides and a diastereomeric mixture of α,β:γ,δ-diepoxides were obtained in each case, and
Antibacterials and antimycotics: Part 1: Synthesis and activity of 2- pyrazoline derivatives
Nauduri, Dhananjaya,Reddy, Gopu Bala Show
, p. 1254 - 1260 (2007/10/03)
A series of 3-styryl-1,5-diphenyl and 5-styryl-1,3-diphenyl 2- pyrazolines of different substitutions has been synthesized by condensation of substituted α,β-unsaturated ketones with phenylhydrazine hydrochloride in presence of catalytic amount of concentrated HCl. Compounds in the 3- styryl series had OMe, NMe2, NO2, OH and isopropyl substituents and those in the 5-styryl series had OMe, NMe2 and NO(s). The 3-styryl-1,5-diphenyl compounds showed little variation in antibacterial activity towards gram- positive and gram-negative bacteria in terms of geometric mean minimum inhibitory concentrations (MIC). The 4',4-NMe2, 4',4-NO2 and 4',4-OMe compounds were found to possess the highest activity in the series. The 5- styryl-1,3-diphenyl series showed lower activities than the 3-styryl series. The in vitro antimycotic activity of the 4',4-OH and 2',2-OH substituted compounds showed good activity than the other molecules in the two series.
