377089-24-2

Basic information

• Product Name: (S)-4-[3,4-Bis-(4-methoxy-benzyloxy)-furan-2-yl]-2,2-dimethyl-[1,3]dioxolane
• Synonyms: (S)-4-[3,4-Bis-(4-methoxy-benzyloxy)-furan-2-yl]-2,2-dimethyl-[1,3]dioxolane
• CAS NO: 377089-24-2
• Molecular Weight: 440.493
• Mol File: 377089-24-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-[3,4-Bis-(4-methoxy-benzyloxy)-furan-2-yl]-2,2-dimethyl-[1,3]dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-[3,4-Bis-(4-methoxy-benzyloxy)-furan-2-yl]-2,2-dimethyl-[1,3]dioxolane(377089-24-2)
• EPA Substance Registry System: (S)-4-[3,4-Bis-(4-methoxy-benzyloxy)-furan-2-yl]-2,2-dimethyl-[1,3]dioxolane(377089-24-2)

Safety Data

• Hazardous Substances Data: 377089-24-2(Hazardous Substances Data)

Upstream product

• 377089-20-8 (R)-5-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3,4-bis-(4-methoxy-benzyloxy)-5H-furan-2-one 

Downstream Products

• 377089-20-8 (R)-5-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3,4-bis-(4-methoxy-benzyloxy)-5H-furan-2-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 50-81-7 ascorbic acid 

Relevant articles and documents

Self-sensitized photooxygenation of 3,4-dialkoxyfurans to vitamin C or its derivatives

Self-sensitized photooxygenation of 3,4-dialkoxyfurans 3a-d with molecular oxygen and UV- or sunlight at room temperature gave vitamin C derivatives 2a-d in good to excellent yields. Furan 3c, having photodegradable protecting groups, was also photooxygenated to give L-ascorbic acid (1) in a "one-pot" reaction. Furthermore, a novel photolytic transformation was developed for deuteration of furan 3b at the C-2 position with D2O to give furan 3d in 95% yield. Toxicity of furans 3a-c and butenolides 2a-c against human embryonic cell, murine embryo fibroblasts, normal fibroblasts, HeLa, and Vero cell lines in the presence of oxygen and indirect solar light was found to be much less than those of the antipsoriasis drugs anthralin and 8-methoxypsoralen.