3775-05-1Relevant articles and documents
NOVEL PYRIDOPYRIMIDINONE COMPOUNDS FOR MODULATING THE CATALYTIC ACTIVITY OF HISTONE LYSINE DEMETHYLASES (KDMS)
-
Page/Page column 98-99, (2016/05/19)
The present invention provides a compound of Formula (I) being capable of modulating the activity of histone lysine demethylase (KDM), pharmaceutical compositions thereof, methods to prepare the said compounds, and the use of such compounds as a medicament. The compound of Formula (I) acts as KDM inhibitor with marked potency, thereby having an outstanding potential for a pharmaceutical intervention of cancer and any other diseases related to KDM dysregulation.
Erratum: Design, synthesis and evaluation of aspirin analogues having an additional carboxylate substituent for antithrombotic activity (Bioorganic and Medicinal Chemistry Letters (2009) 19 (4213-4216))
Alagha, Ahmed,Moman, Edelmiro,Adamo, Mauro F.A.,Nolan, Kevin B.,Chubb, Anthony J.
supporting information, p. 398 - 398 (2015/02/18)
-
Salicylic acid derivatives, processes for their preparation, compositions comprising them, their use
-
, (2008/06/13)
Salicylic acid derivatives of the formula I, where the index and the substituents have the following meanings: X is halogen, NO2, cyano, alkyl or alkoxy; m is 0, 1, 2 or 3, it being possible for the substituents X to be different from each othe