3775-15-3

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.
2. Heterocyclic organic compound

Explanation

It is an organic compound containing a ring structure with atoms of different elements, in this case, carbon, nitrogen, and sulfur.
3. Five-membered ring

Explanation

The compound has a ring structure consisting of five atoms.
4. Contains sulfur and nitrogen atoms

Explanation

The ring structure includes a sulfur atom and two nitrogen atoms, which contribute to its unique properties.
5. Potential applications in organic synthesis and materials science

Explanation

The compound's structure and properties make it a useful building block for creating various organic compounds, including pharmaceuticals and agrochemicals.
6. Used as a building block in pharmaceuticals and agrochemicals

Explanation

Its unique structure allows it to be incorporated into the synthesis of various compounds used in the pharmaceutical and agrochemical industries.
7. Studied for potential as a corrosion inhibitor

Explanation

Research is being conducted to determine if the compound can be used to prevent or reduce the corrosion of metals.
8. Component in optoelectronic devices

Explanation

The compound's properties are being investigated for potential use in optoelectronic devices, which involve the interaction of light with electronic components.
9. Ongoing research

Explanation

Further studies are being conducted to better understand the properties and potential applications of 1,2,5-Thiadiazole, 3,4-diphenyl-, 1,1-dioxide.
10. Interest for chemists and materials scientists

Explanation

The compound's unique structure and potential applications make it an area of interest for researchers in the fields of chemistry and materials science.

Upstream product

• 134-81-6 benzil 
• 7803-58-9 SULFAMIDE 
• 100-52-7 benzaldehyde 
• 492-70-6 1,2-diphenyl-1,2-ethanediol 

Downstream Products

• 3775-17-5 3,4-diphenyl 1,2,5-thiadiazolidine 1,1-dioxide 

Relevant academic research and scientific papers

ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE

An organic electroluminescent device includes a first electrode, a hole transport region provided on the first electrode, an emission layer provided on the hole transport region, an electron transport region provided on the emission layer, and a second electrode provided on the electron transport region, wherein the emission layer includes an organometallic compound represented by Formula 1.

HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME

An organic light-emitting device and a heterocyclic compound, the device including a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode and including an emission layer, wherein the emission layer includes a compound represented by Formula 1A or a compound represented by Formula 1B:

Solvent-Free Condensation Reactions to Synthesize Five-Membered Heterocycles Containing the Sulfamide Fragment

We report a study of the solvent-free condensation reaction of 1,2-dicarbonyl compounds with sulfamide catalyzed by a Keggin-type acid (H3PMo12O40·nH2O, MPA) to obtain 3,4-disubstituted 1,2,5-thiadiazole 1,1-dioxide derivatives. Some reactions were also performed in solution or using nano-sized silica-supported MPA catalyst in order to compare the results under different experimental conditions. Effects of the temperature used for the thermal pretreatment of the catalyst, the reaction temperature, the molar ratios sulfamide/1,2-dicarbonyl compound and MPA/1,2-dicarbonyl compound, and alternative experimental procedures on the yield of the reaction product were investigated. Under suitable experimental conditions eight compounds were obtained in good yields. The catalyst was recycled and reused, but with some loss of its catalytic activity. The presented synthetic method is a simple, clean, and environmentally friendly alternative for synthesizing different 1,2,5-thiadiazole 1,1-dioxide derivatives.

Microwave-assisted synthesis of some substituted sulfamides

Microwave-assisted synthesis of some substituted open-chain and cyclic sulfamides, by amine-exchange reaction, was studied in a modified domestic microwave oven. Reaction times and yields under microwave radiation were compared with classical heating. Synthesis of the sulfamides under microwave irradiation gave better yields with the desired compounds, and in considerably reduced reaction times, than those obtained by classical heating. [Supplementary materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfer, and Silicon and the Related Elements for the following free supplemental files: Additional figures.]

The Isomerization of Allylrhodium Intermediates in the Rhodium-Catalyzed Nucleophilic Allylation of Cyclic Imines

Allylrhodium species generated from potassium allyltrifluoroborates can undergo isomerization by 1,4-rhodium(I) migration to give more complex isomers, which then react with cyclic imines to provide products with up to three new stereochemical elements. High enantioselectivities are obtained using chiral diene-rhodium complexes. Rhodium dance: Allylrhodium species generated from potassium allyltrifluoroborates can undergo isomerization by a 1,4-rhodium(I) migration to give more complex isomers, which then react with cyclic imines to provide products with up to three new stereochemical elements. High enantioselectivities are obtained with chiral diene-rhodium complexes.

Enantioselective synthesis of 3,4-disubstituted cis- and trans-1,2,5-thiadiazolidine-1,1-dioxides as precursors for chiral 1,2-diamines

Both, cis- and trans-3,4-disubstituted thiadiazolidines 5 and 6 can enantioselectively be obtained from thiadiazoles 2 which, in turn, are efficiently prepared from the respective 1,2-diketone by an improved protocol. An asymmetric ruthenium-catalyzed transfer hydrogenation followed by a diastereoselective hydride addition furnishes exclusively the cis-isomers 5 which, under acidic conditions, undergo a novel isomerization into the trans-isomers 6. These cyclic sulfamides can be transformed into 1,2-diamines as well as 2,3-diamino acids.

Synthesis of an α-amino nitrile and a bis α-amino nitrile derivative of thiadiazole: Reaction mechanism

The first nucleophilic addition of an inorganic nucleophile (cyanide) to the activated, rigid, α-diazomethine groups of a 1,2,5-thiadiazole 1,1-dioxide is reported here. An α-amino nitrile and a bis a-amino nitrile derivatives were obtained in good yields (62 and 98%, respectively) and characterized by spectroscopic, analytical, and single crystal X-ray diffraction techniques. The course of the reaction, followed by cyclic voltammetry (CV), showed that cyanide adds to only one of the two C=N double bonds of the thiadiazole, forming an anion from which an N-methyl derivative was obtained. Adequate concentrations of cyanide and methyl iodide (MeI) produced directly the bis a-amino nitrile derivative. Copyright

Reactions of the activated, rigid, α-diazomethine group of 1,2,5-thiadiazole 1,1-dioxides with nitrogenated nucleophiles. Part III: Aliphatic monoamines and phenylhydrazine

The reactions of n-butylamine (BuNH2), 2-aminoethanol (H 2N(CH2)2OH), diethylamine (Et2NH), and phenylhydrazine (PhN2H3) with 3,4-diphenyl-(1a) and phenanthro[9,10-c]-1,2,5-thiadiazole 1,1-dioxide (1b) were studied by cyclic voltammetry (CV) and 1H- and 13C-NMR in aprotic solvent solution. The course of the reactions depended on the substrate-nucleophile combination: Et2NH added to 1a or 1b, forming the corresponding thiadiazolines in an equilibrium monoaddition reaction. The equilibrium constants were evaluated and compared. With primary amines and PhN 2H3, the nucleophile added to both C=N double bonds of 1a and displaced the sulfamide moiety. In the case of the reaction of la with PhN2H3, the intermediate monoaddition thiadiazoline, 3-(2-phenylhydrazino)-3,4-diphenyl-1,2,5-thiadiazoline 1,1-dioxide, was also isolated. BuNH2 and H2N(CH2)2OH reacted with la to give α-bis-imines, while la with PhN2H 3 gave the α-bis-hydrazone. The configurations of benzil bis(ethanolimine) and benzilosazone were determined by single crystal x-ray diffraction analysis as Z,Z. BuNH2 and PhN2H3 reduced 1b to the corresponding thiadiazoline compound 1bH2. Copyright

Heterocyclic compounds as P2X7 ion channel blockers

The present invention relates to a novel series of 4,5-diphenyl-2-amino-4,5-dihydro-imidazole derivatives of the formula II: 1 wherein R, R1, R2, R3, R4, R5, X and Y are as defined herein. This invention also relates to methods of making these compounds. The compounds of this invention are P2X7 ion channel blockers and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases having an inflammatory component, including inflammatory bowel disease, rheumatoid arthritis and disease conditions associated with the central nervous system, such as stroke, Alzheimer''s disease, etc.