3,4-Diphenyl-1,2,5-thiadiazole 1,1-dioxide

Base Information

• Chemical Name: 3,4-Diphenyl-1,2,5-thiadiazole 1,1-dioxide
• CAS No.: 3775-15-3
• Molecular Formula: C14H10N2O2S
• Molecular Weight: 270.312
• DSSTox Substance ID: DTXSID10451408
• Nikkaji Number: J1.101.896C
• Wikidata: Q82271418
• Mol file: 3775-15-3.mol

Synonyms:3,4-diphenyl-1,2,5-thiadiazole 1,1-dioxide;3,4-Diphenyl-1,2,5-thiadiazole-1,1-dioxide;3775-15-3;SCHEMBL3253356;DTXSID10451408;WWVPMBQAWGORGS-UHFFFAOYSA-N

Chemical Property of 3,4-Diphenyl-1,2,5-thiadiazole 1,1-dioxide

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 270.04629874
• Heavy Atom Count: 19
• Complexity: 450

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=NS(=O)(=O)N=C2C3=CC=CC=C3

Technology Process of 3,4-Diphenyl-1,2,5-thiadiazole 1,1-dioxide

There total 18 articles about 3,4-Diphenyl-1,2,5-thiadiazole 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

benzil (134-81-6) → 3,4-diphenyl-1,2,5-thiadiazole-1,1-dioxide (3775-15-3)

Guidance literature:

With N,N'-bis(trimethylsilyl)sulfamide; boron trifluoride diethyl etherate; In toluene; at 20 ℃; for 8h; Inert atmosphere;

DOI:10.1021/ol3034753

Reference yield: 82.0%

SULFAMIDE (7803-58-9) + benzil (134-81-6) → 3,4-diphenyl-1,2,5-thiadiazole-1,1-dioxide (3775-15-3)

Guidance literature:

With molybdophosphoric acid hydrate; In neat (no solvent); at 70 ℃; for 144h; under 760.051 Torr; Temperature; Time; Solvent; Concentration;

DOI:10.1055/s-0035-1561371

Reference yield:

3-phenethyloxy-3,4-diphenyl-2,3-dihydro-[1,2,5]thiadiazole 1,1-dioxide → 2-phenylethanol (60-12-8) + 3,4-diphenyl-1,2,5-thiadiazole-1,1-dioxide (3775-15-3)

Guidance literature:

In acetonitrile; at 25 ℃; Equilibrium constant;

DOI:10.1002/1099-1395(200005)13:5<272::AID-POC241>3.0.CO;2-Y

upstream raw materials:

benzil

Downstream raw materials:

3,4-diphenyl 1,2,5-thiadiazolidine 1,1-dioxide