2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid, also known as fenamic acid, is a pyrimidine derivative with the molecular formula C12H9N3O4. It features a phenyl group attached to the pyrimidine ring and a carboxylic acid group, which contributes to its diverse pharmacological properties.
37804-34-5
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Basic information
- Product Name: 2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid
- Synonyms:
- CAS NO:37804-34-5
- Molecular Formula:
- Molecular Weight: 232.196
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid(CAS DataBase Reference)
- NIST Chemistry Reference: 2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid(37804-34-5)
- EPA Substance Registry System: 2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid(37804-34-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 37804-34-5(Hazardous Substances Data)
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37804-34-5 Usage
Uses
Used in Pharmaceutical Industry:2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid is used as a non-steroidal anti-inflammatory drug (NSAID) for its analgesic, anti-inflammatory, and antipyretic properties. It is particularly effective in relieving pain and reducing inflammation associated with conditions such as arthritis, menstrual cramps, and mild to moderate headaches.
Used in Antitumor Applications:
Fenamic acid has demonstrated potential antitumor activities, making it a candidate for further research and development in oncology. Its mechanism of action and specific applications in cancer treatment are areas of ongoing investigation.
Used in Antimicrobial Applications:
2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid has also shown antimicrobial properties, suggesting its potential use in the development of new antibiotics or as an adjunct to existing treatments for bacterial infections.
However, it is important to note that 2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid can have side effects, and its use should be carefully considered and monitored under medical supervision.
Check Digit Verification of cas no
The CAS Registry Mumber 37804-34-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,8,0 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.Calculate Digit Verification of CAS Registry Number 37804-34:
(7*3)+(6*7)+(5*8)+(4*0)+(3*4)+(2*3)+(1*4)=125
125 % 10 = 5
So 37804-34-5 is a valid CAS Registry Number.
37804-34-5Upstream product
37804-34-5Downstream Products
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2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid
