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4-Methoxy-2-methyl-benzofuran is an organic compound with the chemical formula C10H10O2. It is a derivative of benzofuran, which is a heterocyclic aromatic compound consisting of a benzene ring fused to a furan ring. The molecule features a methyl group (-CH3) at the 2-position and a methoxy group (-OCH3) at the 4-position, attached to the benzene ring. Benzofuran, 4-methoxy-2-methyl- is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals due to its unique structure and properties. It is typically synthesized through various chemical reactions and can be used as an intermediate in the production of more complex molecules.

3781-89-3

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3781-89-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3781-89-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,8 and 1 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3781-89:
(6*3)+(5*7)+(4*8)+(3*1)+(2*8)+(1*9)=113
113 % 10 = 3
So 3781-89-3 is a valid CAS Registry Number.

3781-89-3Downstream Products

3781-89-3Relevant academic research and scientific papers

Facile construction of the benzofuran and chromene ring systems via Pd II-catalyzed oxidative cyclization

So, Won Youn,Jeong, Im Eom

, p. 3355 - 3358 (2007/10/03)

(Chemical Equation Presented) We herein report the development of one-pot procedures for the conversion of allyl aryl ethers to 2-methylbenzofurans (via sequential Claisen rearrangement and oxidative cyclization) and for the conversion of aryl homoallyl e

Cesium Fluoride-Mediated Claisen Rearrangements of Phenyl Propargyl Ethers: Effect of a Substituent on the Phenyl Ring on the Rearrangement

Ishikawa, Tsutomu,Nagai, Keiko,Ohkubo, Naoko,Ishii, Hisashi

, p. 371 - 380 (2007/10/02)

Methoxy or methoxycarbonyl-substituted phenyl propargyl ethers were subjected to Claisen rearrangement either in the absence or in the presence of CsF.Substituent effect on the cyclization is discussed.

Nucleophilic Aromatic Substitution on Tricarbonylchromium-complexed Haloarenes: Synthesis of O-Aryloximes and Their Cyclization to Benzofurans

Alemagna, Andreina,Baldoli, Clara,Buttero, Paola Del,Licandro, Emanuela,Maiorana, Stefano

, p. 192 - 196 (2007/10/02)

A series of O-aryloximes have been prepared from tricarbonylchromium-complexed haloarenes in mild conditions.Title compounds are starting materials for benzofuran synthesis.

Aromatic Nucleophilic Substitution on Cr(CO)3-Complexed Halogenoarenes: A New Synthesis of O-Aryloximes and Their Cyclization to Benzofurans

Alemagna, Andreina,Baldoli, Clara,Buttero, Paola Del,Licandro, Emanuela,Maiorana, Stefano

, p. 417 - 418 (2007/10/02)

O-Aryloximes are synthesized by reaction of acetone oxime with Cr(CO)3-complexed halogenoarenes and then cyclized to give benzofurans.

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