378186-96-0

Usage

Yellow liquid

2,3-Butadien-1-one, 1-(4-bromophenyl)is a yellow liquid, meaning it has a visible color and is in a liquid state at room temperature.

Pungent odor

This chemical has a pungent odor, meaning it has a strong and possibly unpleasant smell.

Building block for various compounds

It is primarily used in organic synthesis as a building block for various compounds, meaning it can be used as a starting material to create other chemical compounds.

Use in pharmaceuticals

This chemical is also known for its use in the production of pharmaceuticals, meaning it can be used to create medications.

Potential use in new materials

2,3-Butadien-1-one, 1-(4-bromophenyl)has potential use in the development of new materials with desired properties, meaning it can be used to create new and improved materials.

Hazardous if not used and stored properly

It is important to handle 2,3-Butadien-1-one, 1-(4-bromophenyl)- with care as it can be hazardous if not used and stored properly, meaning it can pose a risk to health or the environment if not handled correctly.

Upstream product

• 6048-21-1 4-bromobenzoyl cyanide 
• 106-96-7 propargyl bromide 
• 94612-95-0 1-(p-bromophenyl)-but-3-yn-1-ol 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 14297-34-8 2-(p-bromophenyl)furane 
• 1332524-88-5 (E)-2-benzyl-5-(4-bromophenyl)-3-methyl-5-oxopent-2-enenitrile 
• 1332524-86-3 (Z)-2-benzyl-5-(4-bromophenyl)-3-methyl-5-oxopent-2-enenitrile 
• 1332524-68-1 (Z)-5-(4-bromophenyl)-2,3-dimethyl-5-oxopent-2-enenitrile 
• 1332524-70-5 (E)-5-(4-bromophenyl)-2,3-dimethyl-5-oxopent-2-enenitrile 
• 1332524-35-2 1-(4-bromobenzoyl)-4-(4-bromophenyl)-3-cyano-2,6-dimethylbenzene 
• 1364681-75-3 4-(4-bromophenyl)-6-methyl-2H-pyran-2-one 
• 1432479-23-6 C₁₆H₁₅BrO₄ 
• 1432479-40-7 C₂₆H₂₂Br₂O₅ 
• 56961-07-0 4'-bromo-3-methyl-1,1'-biphenyl 
• 1454271-70-5 (E)-1-(4-bromophenyl)-3-fluorobut-2-en-1-one 
• 1454271-89-6 (Z)-1-(4-bromophenyl)-3-fluorobut-2-en-1-one 
• 20511-04-0 (E)-4-(4-bromophenyl)but-3-ene-2-one 
• 1580528-79-5 7-(4-bromophenyl)-5-methylpyrazolo[1,5-a]pyrimidine 

Relevant academic research and scientific papers

Synthesis of vinylic sulfones in aqueous media

A green method for the sulfination of allenic carbonyl compounds to access a wide variety of vinylic sulfones is developed. This reaction works in aqueous media under very mild conditions. This reaction is atom economic. A wide variety of vinylic sulfones could be obtained in moderate to excellent yields with wide functional group tolerance. The efficiency of this method is demonstrated in some reactions where the desired products can be isolated by filtration.

Revisiting the Addition of in-situ Nucleophiles to Allenic Ketones: An Entry Towards Synthesis of Benzodioxins

The manuscript delineates a revisit towards regioselective addition of in situ generated negative nucleophiles to allenic ketones in the presence of a base. A wide variety of allenic ketones as well as nucleophiles are viable in this transformation. A dir

A bicyclization reaction with two molecular allenyl ketones and isocyanides: Synthesis of a lactone-containing azaspirocycle derivative

A novel bicyclization reaction of two molecular allenyl ketones and isocyanides has been disclosed. This strategy allows for the construction of structurally complex spirocyclic lactam-lactone systems in an efficient manner. This protocol also demonstrate

Room temperature Fe(NO3)3·9H 2O/TEMPO/NaCl-catalyzed aerobic oxidation of homopropargylic alcohols

A practical and eco-friendly aerobic oxidation of homopropargylic alcohols using Fe(NO3)3·9H2O/TEMPO/NaCl as catalysts at room temperature under atmospheric pressure was developed affording corresponding homopropargylic ke

Synthesis of 1,2-allenic ketones through oxidation of homopropargyl alcohols with CrO3(cat.)/TBHP under MWI

A CrO3 catalyzed oxidation of homopropargyl alcohols with tert-butyl hydroperoxide under microwave irradiation was found to be an efficient and rapid alternative for the preparation of 1,2-allenic ketones. The advantages of this procedure inclu

Tandem reactions of 1,2-allenic ketones leading to substituted benzenes and α,β-unsaturated nitriles

One-pot double Michael addition/intramolecular aldol reaction/ decarboxylation of 1,2-allenic ketones with cyanoacetate offers an efficient and convenient approach to highly functionalized benzenes. With 2-substituted cyanoacetates, the reaction proceeds via a different tandem process to afford α,β-unsaturated nitriles effectively.

Ru(III)-catalyzed oxidation of homopropargyl alcohols in ionic liquid: an efficient and green route to 1,2-allenic ketones

An efficient and environmentally benign synthesis of 1,2-allenic ketones via RuCl3-catalyzed oxidation of homopropargyl alcohols in ionic liquid with tert-butyl hydroperoxide (TBHP) as the oxidant was reported for the first time. With its reasonable efficiency and green nature, this oxidation provides a novel alternative route to 1,2-allenic ketones.

Indium-mediated highly regioselective reaction of prop-2-ynyl bromides with acyl cyanides in aqueous media: A convenient synthesis of allenic and propargylic ketones

Indium-mediated reaction of acyl cyanides 1 with prop-2-ynyl bromides 2 in aqueous media occurs regioselectively to afford either allenic 3 or propargylic ketones 4 depending on the γ-substituent of the prop-2-ynyl bromide under the mild conditions.