52063-43-1

Basic information

• Product Name: 5-(4-bromophenyl)-3-methylisoxazole
• Synonyms: 5-(4-bromophenyl)-3-methylisoxazole
• CAS NO: 52063-43-1
• Molecular Formula: C₁₀H₈BrNO
• Molecular Weight: 238.08062
• Mol File: 52063-43-1.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(4-bromophenyl)-3-methylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-bromophenyl)-3-methylisoxazole(52063-43-1)
• EPA Substance Registry System: 5-(4-bromophenyl)-3-methylisoxazole(52063-43-1)

Safety Data

• Hazardous Substances Data: 52063-43-1(Hazardous Substances Data)

Usage

Uses

5-(4-Bromophenyl)-3-methylisoxazole is used in preparation of Isoxazole compounds as therapeutic Lysophosphatidic Acid receptor antagonists.

Upstream product

• 619-42-1 4-methoxycarbonylphenyl bromide 
• 127-06-0 acetone oxime 
• 99-90-1 para-bromoacetophenone 
• 378186-96-0 1-(4-bromophenyl)-2,3-butadien-1-one 
• 178261-64-8 1-(4-bromophenyl)-3-(dimethylamino)but-2-en-1-one 

Downstream Products

• 1056456-11-1 3-methyl-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)isoxazole 

Relevant articles and documents

Monohydrochloride Assisted Synthesis of Functionalized Isoxazoles and Pyrazoles from Allenic Ketones: First Synthesis of (Z)-2-Methyl-7H-benzo[b]pyrazolo[5,1-d][1,5]oxazocines

A facile hydrochloride promoted regioselective synthesis of isoxazoles and pyrazoles from 1,2-allenic ketones is reported. The reaction has been scaled up to gram scale. A direct 8-endo dig ring annulations towards the first synthesis of (Z)-2-methyl-7H-b

Clean and efficient synthesis of isoxazole derivatives in aqueous media

A series of 5-arylisoxazole derivatives were synthesized via the reaction of 3-(dimethyl-amino)-1-arylprop-2-en-1-ones with hydroxylamine hydrochloride in aqueous media without using any catalyst. This method has the advantages of easier work-up, mild rea

NOVEL PHENYLPROPIONIC ACID DERIVATIVES AS PEROXISOME PROLIFERATOR-ACTIVATED GAMMA RECEPTOR MODULATORS, METHOD OF THE SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

The present invention provides a novel phenylpropionic acid derivative and a PPAR-γ modulator comprising the same as an active ingredient. The phenylpropionic acid derivative of the present invention has modulatory action on function of PPAR-γ and then exhibits hypoglycemic, hypolipidemic and insulin resistance-reducing effects on PPAR-mediated diseases or disorders. Therefore, the present invention is prophylactically or therapeutically effective for diabetes and metabolic diseases.