6048-21-1 Usage
Description
4-Bromobenzoyl cyanide, also known as 4-Cyanobenzoyl bromide, is a chemical compound characterized by the molecular formula C8H4BrNO. It presents as a white to off-white crystalline solid, which is insoluble in water but readily soluble in organic solvents. 4-BROMOBENZOYL CYANIDE is recognized for its utility as a reagent in organic synthesis, especially in the creation of pharmaceuticals and agrochemicals, and serves as a versatile building block for the synthesis of a variety of organic compounds such as dyes, pigments, and herbicides. It also finds application in polymer manufacturing and as a precursor in the synthesis of other chemical compounds. Due to its potential hazards, it is crucial to handle 4-Bromobenzoyl cyanide with care, ensuring use in well-ventilated areas and with appropriate personal protective equipment.
Uses
Used in Pharmaceutical Industry:
4-Bromobenzoyl cyanide is used as a reagent for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its role in this industry is pivotal for the creation of compounds with specific medicinal properties.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Bromobenzoyl cyanide is utilized as a reagent in the production of agrochemicals, including herbicides. It aids in the development of compounds designed to control, repel, or kill pests that are harmful to crops.
Used in Dye and Pigment Industry:
4-Bromobenzoyl cyanide is employed as a building block in the synthesis of dyes and pigments, which are essential for coloring various materials in industries such as textiles, plastics, and printing inks.
Used in Polymer Industry:
4-BROMOBENZOYL CYANIDE is also used in the manufacture of certain polymers, where it contributes to the formation of polymeric materials with specific properties, enhancing their performance in various applications.
Used as a Precursor in Chemical Synthesis:
4-Bromobenzoyl cyanide serves as a precursor in the synthesis of other chemical compounds, indicating its importance in the broader scope of chemical production and research.
Check Digit Verification of cas no
The CAS Registry Mumber 6048-21-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,4 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6048-21:
(6*6)+(5*0)+(4*4)+(3*8)+(2*2)+(1*1)=81
81 % 10 = 1
So 6048-21-1 is a valid CAS Registry Number.
6048-21-1Relevant articles and documents
A Cyanide-Free Synthesis of Acylcyanides through Ru-Catalyzed C(sp3)-H-Oxidation of Benzylic Nitriles
Eisele, Pascal,Bauder, Michael,Hsu, Shih-Fan,Plietker, Bernd
, p. 689 - 691 (2019/05/07)
A practical method for generation of acylcyanides devoid of any external cyanide sources is presented that relies on a mild Ru-catalyzed selective C?H-oxidation of benzylic nitriles. The starting materials are smoothly generated through condensation of the corresponding carboxylic acid amides using silanes. The obtained acylcyanides can be employed in a plethora of transformation as exemplified to some larger extend in the sequence of C?H-oxidation-Tischenko-rearrangement for the generation of structurally diverse benzoyloxycyanohydrines.
Acceptorless and Base-free Dehydrogenation of Cyanohydrin with (η6-Arene)halide(Bidentate Phosphine)ruthenium(II) Complex
Kim, Kicheol,Moeljadi, Adhitya Mangala Putra,Hirao, Hajime,Hong, Soon Hyeok
, p. 3292 - 3298 (2017/09/06)
Ruthenium-catalyzed dehydrogenation of cyanohydrins under acceptorless and base-free conditions was demonstrated for the first time in the synthesis of acyl cyanide. As opposed to the thermodynamically preferred elimination of hydrogen cyanide, the dehydrogenation of cyanohydrins could be kinetically controlled with ruthenium (II) bidentate phosphine complexes. The effects of the arene, phosphine ligands and counter anions were investigated in regard to catalytic activity and selectivity. Selective dehydrogenation can occur via β-hydride elimination with the experimentally observed [(alkoxide)Ru] complex. (Figure presented.).
Synthesis of benzoyl cyanide through aerobic photooxidation of benzyl cyanide using carbon tetrabromide as a catalyst
Sugiura,Tachikawa,Nagasawa,Tada,Itoh
, p. 70883 - 70886 (2015/09/08)
We developed a synthetic method toward benzoyl cyanide through aerobic photooxidation of benzyl cyanide in the presence of carbon tetrabromide under visible light irradiation with fluorescent lamps.
