37847-24-8

Usage

Uses

Used in Fragrance Industry:
ETHYL 3-ACETYLBENZOATE is used as a fragrance ingredient for its pleasant floral scent, contributing to the creation of various perfumes, colognes, and other scented products. Its aromatic properties make it a valuable component in the formulation of personal care and household products, enhancing the sensory experience for consumers.
Used in Chemical Research:
In the field of chemical research, ETHYL 3-ACETYLBENZOATE serves as a valuable compound for studying the properties and reactions of benzoic acid esters. Its chemical structure and reactivity provide insights into the behavior of similar compounds, aiding in the development of new synthetic pathways and applications in organic chemistry.

InChI:InChI=1/C11H12O3/c1-3-14-11(13)10-6-4-5-9(7-10)8(2)12/h4-7H,3H2,1-2H3

Upstream product

• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 95-92-1 oxalic acid diethyl ester 
• 586-42-5 3-acetylbenzoic acid 
• 75-03-6 ethyl iodide 
• 1609-47-8 diethyl dicarbonate 
• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 
• 58313-23-8 3-iodobenzoic acid methyl ester 
• 917-54-4 methyllithium 

Downstream Products

• 105640-23-1 ethyl 3-isopropenylbenzoate 
• 1455472-93-1 3-[(1S)-2-[(3S)-3-[(tert-butyldimethylsilyl)oxy]pyrrolidin-1-yl]-1-(methylamino)ethyl]-N,N-dimethylbenzamide 
• 1455472-91-9 3-[(1S)-2-[(3S)-3-[(tert-butyldimethylsilyl)oxy]pyrrolidin-1-yl]-1-(methylamino)ethyl]benzoic acid 
• 1455472-89-5 ethyl 3-[(1S)-2-[(3S)-3-[(tert-butyldimethylsilyl)oxy]pyrrolidin-1-yl]-1-(methylamino)ethyl]benzoate 
• 1455472-87-3 ethyl 3-[(1S)-2-[(3S)-3-[(tert-butyldimethylsilyl)oxy]pyrrolidin-1-yl]-1-hydroxyethyl]benzoate 
• 1455472-86-2 ethyl 3-[(2S)-oxiran-2-yl]benzoate 
• 1455472-85-1 ethyl 3-[(1S)-2-bromo-1-hydroxyethyl]benzoate 
• 1455472-84-0 3-[(1S)-2-[(3S)-3-[(tert-butyldimethylsilyl)oxy]pyrrolidin-1-yl]-1-(methylamino)ethyl]-N-(2,2,2-trifluoroethyl)benzamide 
• 914202-62-3 ethyl 2-amino-4-[3-(ethoxycarbonyl)phenyl]thiophene-3-carboxylate 
• 586-42-5 3-acetylbenzoic acid 
• 40912-34-3 3-(1-hydroxy-1-methylethyl)benzoic acid 

Relevant academic research and scientific papers

Diethyloxalate as “CO” Source for Palladium-Catalyzed Ethoxycarbonylation of Bromo- and Chloroarene Derivatives

Palladium(II)-catalyzed ethoxycarbonylation of aryl bromides with diethyloxalate oxalate is described. Functionalized aromatic esters can be efficiently synthesized with only 0.65 mol % PdCl2(PPh3)2 catalyst under microwav

Hydroxypurine compound and use thereof

The invention discloses a hydroxypurine compound and a use of the hydroxypurine compound as a PDE2 or TNFa inhibitor and concretely discloses a compound shown in the formula (I) and its tautomer or pharmaceutically acceptable salt.

Palladium-Catalyzed Carbonylations of Arylboronic Acids: Synthesis of Arylcarboxylic Acid Ethyl Esters

An approach for the palladium-catalyzed ethoxycarbonylations of arylboronic acids using diethyl pyrocarbonate as carbon monoxide/carbon dioxide (CO/CO2) surrogate in moderate to good yields has been investigated.

SUBSTITUTED HETEROCYCLIC ACETAMIDES AS KAPPA OPIOID RECEPTOR (KOR) AGONISTS

The present invention relates to a series of substituted compounds having the general formula (I), including their ste reoisomers and/or their pharmaceutically acceptable salts, wherein R1, R2, R3. R4, R5, and R6 are as defined herein. This invention also relates to methods of making these compounds including intermediates. The compounds of this invention are effective at the kappa (κ) opioid receptor (KOR) site. Therefore, the compounds of this invention are useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of central nervous system disorders (CNS), including but not limited to acute and chronic pain, and associated disorders, particularly functioning peripherally at the CNS.

HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF

The present invention provides a novel amide compound represented by the following formula, which has a matrix metalloproteinase inhibitory activity and is useful as a pharmaceutical agent. wherein each symbol is as defined in the specification.

Highly efficient Pd-catalyzed carbonylative cross-coupling reactions with tetraorganoindates

Tetraorganoindates, which were prepared easily from the reaction of 1 equiv of InCl3 with 4 equiv of organometallics, could be employed as effective nucleophilic cross-coupling partners in Pd-catalyzed carbonylative cross-coupling reactions with a variety of organic electrophiles. The present method gave unsymmetrical ketones and 1,4-diacylbenzenes in good yields with highly efficient transfer of almost all the organic groups attached to the indium under a carbon monoxide atmosphere in THF at 60 °C.

Pd-catalyzed carbonylative cross-coupling reactions by triorganoindiums: Highly efficient transfer of organic groups attached to indium under atmospheric pressure

(Matrix presented) A highly atom-efficient synthetic method of unsymmetrical ketones was developed by using trialkyl- and triarylindiums, which could be employed as effective cross-coupling partners in Pd-catalyzed carbonylative cross-coupling reactions with a variety of organic electrophiles. The present method produced unsymmetrical ketones and 1,4-diacylbenzenes in good yields with highly efficient transfer of almost all the organic groups attached to the indium under atmospheric pressure of CO gas in THF at 66°C.

SUBSTITUTED THIAZOLE DERIVATIVES BEARING 3-PYRIDYL GROUPS, PROCESS FOR PREPARING THE SAME AND USE THEREOF

The present invention provides a pharmaceutical composition having a steroid C17,20-lyase inhibitory activity, which is useful as a prophylactic or therapeutic agent of prostatism, tumor such as breast cancer and the like, more particularly, a steroid C17,20-lyase inhibitor containing a compound represented by the formula: wherein A1 is an aromatic hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, one of A2 and A3 is a hydrogen atom, a halogen atom, a C1-4 aliphatic hydrocarbon group optionally having substituents or an optionally esterified carboxyl group, the other of A2 and A3 is an aromatic hydrocarbon group optionally having substituents or a heterocyclic group optionally having substituents, and at least one of A1, A2 and A3 is a 3-pyridyl group optionally having substituents, or a salt thereof or a prodrug thereof.