37857-41-3Relevant academic research and scientific papers
Regularities of the amino-Claisen rearrangement mechanism
Abdrakhmanov,Borisov,Ismagilov,Nigmatullin,Khusnitdinov,Tolstikov
, p. 83 - 87 (2013)
The synthetic and kinetic regularities of the amino-Claisen rearrangement (ACR) were studied for the transformation of 2,5-dimethyl-N-(pent-3-en-2-yl) aniline. The ACR products are formed due to the conversion of a binary π-complex formed by the reaction of N-alkenylaniline hydrochloride with hydrochloride of the solvent (2,5-dimethylaniline).
Synthesis of (1′S*,2R*,3R*)- and (1′S*,2R*,3S*)-N-arylsulfonyl-2-(1′-halogenethyl)-3-methylindolines and their selective toxicity against SH-SY5Y cell line
Gataullin, Rail R.,Maksimova, Marina A.,Vakhitova, Yuliya V.,Zainullina, Liana F.,Zileeva, Zulfia R.
, (2020/01/24)
N-tosyl-2- and N-tosyl-4-halogen-substituted derivatives of 2-(1-methylbut-2-en-1-yl)aniline were synthesized and their molecular iodine-mediated cyclization was investigated. The cyclization upon interaction of N-tosyl-6-methyl-2-(1-methylbut-2-en-1-yl)a
A modular approach to α,β-unsaturated N-aryl ketonitrones
Hood, Tyler S.,Bryan Huehls,Yang, Jiong
, p. 4679 - 4682 (2012/09/05)
A modular approach to α,β-unsaturated N-aryl ketonitrones has been developed. Specifically, condensation of anilines and enals followed by alkylation of the resulting α,β-unsaturated imines provided N-allyl anilines, which were subjected to oxidation with
Stereoselective reduction of enaminones to syn γ-aminoalcohols
Bartoli, Giuseppe,Cupone, Giovanna,Dalpozzo, Renato,De Nino, Antonio,Maiuolo, Loredana,Procopio, Antonio,Tagarelli, Antonio
, p. 7441 - 7444 (2007/10/03)
One-pot reduction of enaminones to syn γ-aminoalcohols can be efficiently performed by lithium borohydride in the presence of cerium chloride as Lewis acid. Selectivities are very good with respect to classical reduction method of these products.
Synthesis of Aryl-Substituted Propanols, Pentanediols, and Tetrahydropyran
Gataullin,Kazhanova,Galeeva,Fatykhov,Spirikhin,Abdrakhmanov
, p. 106 - 110 (2007/10/03)
Oxidation of N- and C-alkenylanilines with ozone under conditions of alcohol formation was studied. Depending on the structure of the alkenyl moiety, the reaction yields aryl-substituted propanols, pentanediols, or tetrahydropyran.
EFFECTS OF SUBSTITUENTS IN ACID-CATALYZED CLAISEN AMINO REARRANGEMENT
Abdrakhmanov, I. B.,Saraeva, Z. N.,Nigmatullin, N. G.,Komissarov, V. D.,Tolstikov, G. A.
, p. 2117 - 2122 (2007/10/02)
A series of 4-R2-N-R1-N-(1-methyl-2-butenyl)- and 4-R2-N-R1-2-(1-methyl-2-butenyl)-anilines was synthesized.The rate constants of rearrangement and elimination of the hydrochlorides of the 4-R2-N-R1-N-(1-methyl-2-butenyl)anilines in nitrobenzene were measured at 110 and 130 deg C.The correlation equations which describe the effect of the nature of the substituents on the reactivity of the substrate in these reactions and the selectivity of their occurence were established.A mechanism of the processes was proposed.
A NEW SYNTHESIS OF IMIDOYL IODIDES VIA BECKMANN REARRANGEMENT OF OXIME SULFONATES
Ishida, Yasuko,Sasatani, Satoru,Maruoka, Keiji,Yamamoto, Hisashi
, p. 3255 - 3258 (2007/10/02)
A new synthetic method of imidoyl iodides has been devised which involves the Beckmann rearrangement of oxime derivatives with trimethylsilyl iodide or diethylaluminum iodide.This allows a one-pot procedure for α-arylation of amines in synthetically usefu
