7294-89-5

Usage

Uses

Used in Pharmaceutical and Chemical Research:
(3Z)-4-anilinopent-3-en-2-one is used as a research compound for exploring its potential biological activities and applications in the development of new pharmaceutical agents. Its unique structure and functional groups make it a valuable tool in understanding various biological processes and mechanisms.
Used in Organic Chemistry:
In the field of organic chemistry, (3Z)-4-anilinopent-3-en-2-one is used as an intermediate in the synthesis of a wide range of organic compounds. Its presence in various chemical reactions allows for the creation of diverse molecules with different properties and applications.
Used in Chemical Synthesis Industry:
(3Z)-4-anilinopent-3-en-2-one is utilized as a key intermediate in the production of various chemical compounds, contributing to the development of new materials and products across different industries. Its role in chemical synthesis highlights its importance in the advancement of the chemical manufacturing sector.

Upstream product

• 62-53-3 aniline 
• 123-54-6 acetylacetone 
• 27363-79-7 2-n-butylthio-2-penten-4-one 
• 3859-41-4 1,3-cyclopentadione 
• 16195-91-8 N-cyclohexyl-4-amino-3-penten-2-one 
• 59487-13-7 N-tert-butyl-4-amino-3-penten-2-one 
• 1510707-07-9 C₁₀H₁₇NO 
• 64-10-8 phenyl carbamate 
• 59487-11-5 N-isopropyl-4-amino-3-penten-2-one 

Downstream Products

• 14627-91-9 4-anilino-pent-3-en-2-one-phenylimine; hydrochloride 
• 1198-37-4 2,4-dimethylquinoline 
• 5102-18-1 1-(5-hydroxy-2-methyl-1-phenyl-1H-indol-3-yl)ethanone 
• 22293-58-9 4-Anilino-3--3-penten-2-on 
• 51851-42-4 C₂₃H₂₂BNO 
• 18788-15-3 1-Acetyl-2-anilino-propan-2-phosphonigsaeure 
• 54196-35-9 N-phenyl-β-thioketoiminate 
• 2320-67-4 2-acetyl-3-anilino-but-2-enethioic acid anilide 
• 19164-92-2 2-(phenyl)amino-4-(phenyl)imino-2-pentene 
• 2227-93-2 2-acetyl-3-anilino-but-2-enethioic acid benzoylamide 
• 2227-92-1 (2-acetyl-3-anilino-but-2-enethioyl)-carbamic acid phenyl ester 
• 23889-49-8 2-acetyl-3-anilino-but-2-enethioic acid toluene-4-sulfonylamide 
• 83085-35-2 (Z)-4-Phenylamino-3-pyrrolidin-1-ylmethyl-pent-3-en-2-one 
• 83072-66-6 (Z)-4-Phenylamino-3-piperidin-1-ylmethyl-pent-3-en-2-one 

Relevant academic research and scientific papers

Metal coordination compound, intermediate, preparation method and application thereof

The invention discloses a metal coordination compound, an intermediate, a preparation method and application thereof, and provides a metal coordination compound I, which can be independently used forcatalyzing ethylene homopolymerization or used for catal

Synthesis of multilayer polymer-immobilised nanosilver for catalytic study in condensation reaction of aniline and acetylacetone

Abstract: Silver nanoparticles were synthesized in green route with non-hazardous polyvinyl alcohol and polyvinylpyrrolidone as stabilizing as well as reducing agents and water as green solvent. This silver nanoparticle-embedded polymer composite film, Ag/PVA–PVP was characterized by UV–Vis spectroscopy, SEM and TEM. The catalytic activity of this film was evaluated in reduction of p-nitrophenol, acylation of aniline and synthesis of a β-enaminone, 4-phenylamino-pent-3-en-one with appreciably good results. β-enaminone synthesis reaction was chosen to study the effects of kinetic parameters such as reactant quantity, catalyst loading, solvents and temperatures. In a typical reaction, 89% conversion was achieved. A probable chemical reaction mechanism is suggested. Kinetic model fitting for the synthesis of β-enaminone reaction was done for the first time here. Heterogeneous kinetic model following Eley-Rideal pathway showed an excellent data fitting for the reaction. The rate law parameters were estimated. Graphic abstract: Scheme. Synthesis and catalytic application of multilayer polymer-immobilised nanosilver in condensation reaction of aniline and acetylacetone.[Figure not available: see fulltext.].

A novel and reusable magnetic nanocatalyst developed based on graphene oxide incorporated strontium nanoparticles for the facial synthesis of β-enamino ketones under solvent-free conditions

A novel magnetic SrFeGO nanocatalyst (NC) was synthesized through a simple sol–gel technique by introducing strontium and iron oxide nanoparticles onto graphene. The synthesized NC was characterized using FT-IR and FE-SEM. Subsequently, the catalytic activity of SrFeGO was tested in a reaction between β-dicarbonyl compounds and aniline derivatives to gain β-enamino ketone derivatives under solvent-free conditions. It was found that SrFeGO NC is a potential catalyst for the synthesis of β-enamino ketones. The β-enamino ketone produced by such reactions could be isolated in high purity without the need for chromatographic purifications. The newly prepared magnetic graphene oxide nanocomposite could be recovered and reused for numerous times with no significant decrease in efficiency. Moreover, the protocol has the advantages of excellent yielding (up to 98%) in short a reaction time, benefitting an easy workup procedure and being environmentally friendly.

Oxo - nitrided iron complexes, said oxo - nitrided iron complexes including catalyst system, and [khen [khen] [cyu] gay [syen [syen] it became of dienes (hole) for the polymerization method (by machine translation)

The present invention refers to general formula (I) or (II) having oxo - nitrided iron complexes are disclosed. Said general formula (I) or (II) having oxo - [khen [khen] [cyu] gay [syen [syen] it became of dienes (ball) is nitrided iron complexes for the

Metal complex, intermediate, and preparation method and application of metal complex and intermediate

The invention discloses a metal complex, an intermediate, and a preparation method and application of the metal complex and intermediate. The metal complex I can be used for catalyzing ethylene homopolymerization independently or under action of a cocatal

β-Enaminone Synthesis from 1,3-Dicarbonyl Compounds and Aliphatic and Aromatic Amines Catalyzed by Iron Complexes of Fused Bicyclic Imidazo[1,5-a]pyridine Derived N-Heterocyclic Carbenes

A series of Fe–NHC complexes (1–2)c of the fused bicyclic imidazo[1,5-a]pyridine framework of the type [CpFe(2-R-imidazo[1,5-a]pyridin-3-ylidene)(CO)2]BF4 {R = mesityl (1c), nPr (2c)} successfully carried out the synthesis of β-enamino ketones (3–10) and (17–27) and β-enamino esters (11–16) and (28–36) by the condensation of acyclic and cyclic 1,3-dicarbonyl compounds and various aliphatic and aromatic amines in the presence of light irradiation. Quite significantly, the catalytically relevant substrate adduct species of the type [CpFe(NHC)(acac)] (2e) and the product adduct species of the type [CpFe(NHC)(β-enaminone)] (2f) of the Fe–NHC precatalyst (2c) have been detected by mass spectrometry study. The [CpFe(2-R-imidazo[1,5-a]pyridin-3-ylidene)(CO)2]BF4 {R = mesityl (1c), nPr (2c)} complexes were obtained from their respective N–heterocyclic carbene precursors namely, the 2-R-imidazo[1,5-a]pyridin-2-ium chloride {R = mesityl (1a), nPr (2a)} by the reaction with CpFe(CO)2I in the presence of KN(SiMe3)2 followed by the salt metathesis reaction with AgBF4.

Synthesis and coordination chemistry of sterically hindered cobalt(II) β-ketoiminate complexes

The reactions of cobalt(II) chloride with α,β-unsaturated-β-ketoamines, CH3C([dbnd]O)CH[dbnd]C(NHR)CH3, where R = -phenyl, HLPh; R = -mesityl, HLmes; R = -2,6-diisopropylphenyl, HLdipp, and sodium hyd

Immobilization and DFT studies of Tin chloride on UiO-66 metal–organic frameworks as active catalyst for enamination of acetylacetone

An efficient synthetic method for the preparation of β-enaminones catalyzed by immobilization of SnCl2 on Zr-metal–organic frameworks (UiO-66 MOF) and designated as SnUiO66 is described. Also the prepared catalyst was characterized by Fourier t

Redox Non-Innocence and Isomer-Specific Oxidative Functionalization of Ruthenium-Coordinated β-Ketoiminate

This article deals with isomeric ruthenium complexes [RuIII(LR)2(acac)] (S=1/2) involving unsymmetric β-ketoiminates (AcNac) (LR=R-AcNac, R=H (1), Cl (2), OMe (3); acac=acetylacetonate) [R=para-substituents (H,

Citrus juice: Green and natural catalyst for the solvent-free silica supported synthesis of β-enaminones using grindstone technique

Aim and Objective: Citrus Juice as an efficient, cost-effective and green catalyst employed for one-pot synthesis of various β-substituted enaminones through the reaction of β-dicarbonyl compounds with different primary amines in a solvent-free conditions on silica gel as solid surface using grindstone technique in high yields and short reaction times. The presented procedure is operationally simple, practical and green. Material and Methods: The wide application of this procedure is demonstrated by the use of various substituted amines to react with β-dicarbonyl compounds. The method was successfully applied for primary amines (15 entries) and the related enaminones were well synthesized in good to excellent yields. Melting points were measured on an Electro thermal 9100 apparatus. 1HNMR and 13C NMR spectra were recorded on a FTNMR BRUKER DRX 500 Avence spectrometer. Chemical shifts were given in ppm from TMS as internal references and CDCl3 was used as the solvent as well. The IR spectra were recorded on a Perkin Elmer FT-IR GX instrument. The chemicals used in this work were purchased from Merck and Fluka chemical companies. Results: Grinding synthesis of citrus juice catalyzed enamination of 1,3-dicarbonyls (acetylacetone, methyl and ethyl-3-oxobutanoate) with various primary amines (aromatic and aliphatic) under solvent-free silica supported conditions was examined and studied (15 entries) and the obtained enaminones were well synthesized in good to excellent yields. Furthermore, the effect of various catalysts on the yield and reaction time for grinding synthesis of 3-phenylamino-but-2-enoic acid ethyl ester (1) by this method has evaluated as well. Conclusion: a novel, efficient and green protocol for the grinding synthesis of enaminones using citrus juice as natural catalyst has been presented. This methodology is user friendly, green and low cost procedure under mild reaction condition with faster reaction rates. The citrus juice is inexpensive and non-toxic which makes the process convenient, more economic and benign. Furthermore, applying grindstone technique in solvent-free conditions, use of silica gel as a solid and heterogeneous surface in reaction, high yields of products, cleaner reaction profiles, and availability of the reagents makes this method a better choice for synthetic chemists.