37864-28-1Relevant academic research and scientific papers
Coproduct promoted povarov reaction: Synthesis of substituted quinolines from methyl ketones, arylamines, and α-ketoesters
Gao, Qinghe,Liu, Shan,Wu, Xia,Zhang, Jingjing,Wu, Anxin
, p. 5984 - 5991 (2015)
A highly efficient I2-catalyzed Povarov-type reaction of methyl ketones, arylamines, and α-ketoesters is developed. This reaction utilizes a catalytic amount of HI coproduct as a promoter for the synthesis of substituted quinolones. This simple procedure represents an interesting new form of reactivity for the Povarov reaction with good functional group compatibility.
