37872-24-5Relevant academic research and scientific papers
Increased hydrophobicity and estrogenic activity of simple phenols with silicon and germanium-containing substituents
Fujii, Shinya,Miyajima, Yu,Masuno, Hiroyuki,Kagechika, Hiroyuki
, p. 160 - 166 (2013/02/23)
Here, we report the systematic synthesis and characterization of simple phenols bearing a trialkyl(aryl)silyl or trialkyl(aryl)germyl functional group as a hydrophobic substituent. These silicon and germanium analogues exhibited higher hydrophobicity than
COMPOUNDS FOR INHIBITING KSP KINESIN ACTIVITY
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Page/Page column 87-88, (2010/11/23)
The present invention provides compounds of Formula (I) (wherein R1, R3, X, W, Z and ring Y are as defined herein). The present invention also provides compositions comprising these compounds that are useful for treating cellular proliferative diseases or disorders associated with KSP kinesin activity and for inhibiting KSP kinesin activity.
