378766-08-6

Basic information

• Product Name: 2-(4-FLUORO-PHENYL)-7-METHYL-IMIDAZO[1,2-A]PYRIDINE
• Synonyms: 2-(4-FLUORO-PHENYL)-7-METHYL-IMIDAZO[1,2-A]PYRIDINE
• CAS NO: 378766-08-6
• Molecular Formula: C14H11FN2
• Molecular Weight: 226.25
• Mol File: 378766-08-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-FLUORO-PHENYL)-7-METHYL-IMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-FLUORO-PHENYL)-7-METHYL-IMIDAZO[1,2-A]PYRIDINE(378766-08-6)
• EPA Substance Registry System: 2-(4-FLUORO-PHENYL)-7-METHYL-IMIDAZO[1,2-A]PYRIDINE(378766-08-6)

Safety Data

• Hazardous Substances Data: 378766-08-6(Hazardous Substances Data)

Usage

Uses

2-(4-Fluorophenyl)-7-methylimidazo[1,2-a]pyridine

Upstream product

• 329-79-3 1-(4-fluorophenyl)ethanone oxime 
• 403-42-9 1-(4-fluorophenyl)ethanone 

Relevant articles and documents

CuCl2-catalyzed N[sbnd]O bond cleavage of oxime esters: Approach to imidazoheterocycles and furo[3,2-c]chromenyl fused imidazoles

An articulate approach to a diverse set of imidazoheterocycles in good to high yields via a copper-catalyzed aza-annulation of several oxime esters with a group of 2-amino-azaarenes was developed. The above cyclization reaction probably proceeds via a single electron transfer process which embodies a new technique for creating two new C[sbnd]N bonds for imidazole ring synthesis. Gratifyingly, the implementation of this chemistry could be further stretched to the synthesis of a novel class of fused imidazoles bearing a furo[3,2-c]chromene moiety via a sequential C[sbnd]N bond formation, followed by C(sp2)-H functionalization/5-endo-dig-oxacyclization (C[sbnd]C and C[sbnd]O bonds) of in situ produced fused imidazoles with cyclic enynones in the presence of copper(II) as a π-electrophilic Lewis acid catalyst.