37885-76-0

Basic information

• Product Name: ETHYL 2-(TERT-BUTYLAMINO)ACETATE
• Synonyms: ETHYL 2-(TERT-BUTYLAMINO)ACETATE;Glycine, N-(1,1-diMethylethyl)-, ethyl ester
• CAS NO: 37885-76-0
• Molecular Formula: C₈H₁₇NO₂
• Molecular Weight: 159.23
• Mol File: 37885-76-0.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 190.7 °C at 760 mmHg
• Flash Point: 69.2 °C
• Appearance: /
• Density: 0.92 g/cm³
• Vapor Pressure: 0.533mmHg at 25°C
• Refractive Index: 1.427
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ETHYL 2-(TERT-BUTYLAMINO)ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-(TERT-BUTYLAMINO)ACETATE(37885-76-0)
• EPA Substance Registry System: ETHYL 2-(TERT-BUTYLAMINO)ACETATE(37885-76-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 37885-76-0(Hazardous Substances Data)

Usage

General Description

Ethyl 2-(tert-butylamino)acetate, also known as NSC 74753, is a chemical compound that is characterized by the combination of ethyl, acetate, and tertiary-butylamino elements. Its chemical formula is C8H17NO2, and its molecular weight is 159.23 g/mol. ETHYL 2-(TERT-BUTYLAMINO)ACETATE is categorized under the organic compounds known as carboxylic acid esters, specifically the type whose ester group is the acetate group. The compound exhibits a distinct odiferous quality and is available in liquid form. Ethyl 2-(tert-butylamino)acetate is used in a variety of industrial applications, and it is recommended that it should be handled with appropriate safety measures as it could be hazardous if improperly handled.

InChI:InChI=1/C8H17NO2/c1-5-11-7(10)6-9-8(2,3)4/h9H,5-6H2,1-4H3

Upstream product

• 105-39-5 chloroacetic acid ethyl ester 
• 75-64-9 tert-butylamine 
• 623-73-4 diazoacetic acid ethyl ester 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 143159-80-2 N-(1,1-Dimethylethyl)-N-(4-nitrobenzoyl)-aminoacetic acid ethyl ester 
• 107107-46-0 N-(9-Phenanthrylmethyl)-N-tetr-butylglycine hydrochloride 
• 6939-25-9 3-(t-butyl)sydnone 
• 143159-79-9 N-(1,1-Dimethylethyl)-N-(4-nitrobenzoyl)-aminoacetic acid 

Relevant articles and documents

Cyclobutadiene cobalt complexes as catalysts for insertion of diazo compounds into X–H bonds

Novel cyclobutadiene cobalt complex with labile naphthalene ligand [(C4Et4)Co(C10H8)]PF6 catalyzes the insertion of ethyl diazoacetate into X–H bonds giving the corresponding products in 15–75% yields

Solution-Phase Synthesis of Backbone-Constrained Cationic Peptoid Hexamers with Antibacterial and Anti-Biofilm Activities

Abstract: Submonomer synthesis in solution and block-coupling protocols were combined to prepare amphiphilic peptoid hexamers. The amphipathic character arises from the use of hydrophobic aliphatic tert-butyl side-chains imposing the cis-amide backbone co

Exploring the Conformation of Mixed Cis- Trans α,β-Oligopeptoids: A Joint Experimental and Computational Study

The synthesis and conformational preferences of a set of new synthetic foldamers that combine both the α,β-peptoid backbone and side chains that alternately promote cis- and trans-amide bond geometries have been achieved and addressed jointly by experiment and molecular modeling. Four sequence patterns were thus designed and referred to as cis-β-trans-α, cis-α-trans-β, trans-β-cis-α, and trans-α-cis-β. α- and βNtBu monomers were used to enforce cis-amide bond geometries and α- and βNPh monomers to promote trans-amides. NOESY and molecular modeling reveal that the trans-α-cis-β and cis-β-trans-α tetramers show a similar pattern of intramolecular weak interactions. The same holds for the cis-α-trans-β and trans-β-cis-α tetramers, but the interactions are different in nature than those identified in the trans-α-cis-β-based oligomers. Interestingly, the trans-α-cis-β peptoid architecture allows establishment of a larger amount of structure-stabilizing intramolecular interactions.