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<<(2,2,2-trichloroethyl)oxy>carbonyl>-L-proline is a chemical compound consisting of a proline molecule with an attached (2,2,2-trichloroethyl)oxy>carbonyl group. <<(2,2,2-trichloroethyl)oxy>carbonyl>-L-proline is utilized in the synthesis of peptides, where the (2,2,2-trichloroethyl)oxy>carbonyl group serves as an acylation reagent. Its primary function is to protect the amine group of the amino acid, thus preventing unwanted reactions. The selective modification of the proline residue in peptides and proteins is facilitated by the attachment of this group to the proline molecule. Proline, an essential amino acid in proteins, is crucial for their structure and function. The addition of the (2,2,2-trichloroethyl)oxy>carbonyl group to proline enables controlled manipulation and study of proline-containing peptides and proteins in biochemical and biomedical research.

37888-34-9

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37888-34-9 Usage

Uses

Used in Biochemical Research:
<<(2,2,2-trichloroethyl)oxy>carbonyl>-L-proline is used as a protective agent for the amine group of proline in the synthesis of peptides. This protection is crucial for preventing unwanted reactions during peptide synthesis, ensuring the successful formation of the desired peptide sequence.
Used in Biomedical Research:
In biomedical research, <<(2,2,2-trichloroethyl)oxy>carbonyl>-L-proline is used as a selective modification tool for proline residues in peptides and proteins. This selective modification allows researchers to study the effects of proline modification on protein structure, function, and stability, contributing to a deeper understanding of protein biology and its implications in various diseases and conditions.
Used in Pharmaceutical Industry:
<<(2,2,2-trichloroethyl)oxy>carbonyl>-L-proline is also used in the pharmaceutical industry for the development of drugs targeting proline-containing peptides and proteins. By utilizing <<(2,2,2-trichloroethyl)oxy>carbonyl>-L-proline, researchers can design and synthesize novel drug candidates with improved specificity and efficacy, potentially leading to the development of new therapeutics for various diseases.
Used in Drug Delivery Systems:
In the development of drug delivery systems, <<(2,2,2-trichloroethyl)oxy>carbonyl>-L-proline can be employed as a component in the design of targeted drug carriers. By incorporating <<(2,2,2-trichloroethyl)oxy>carbonyl>-L-proline into the structure of drug carriers, it may be possible to enhance the selective delivery of therapeutic agents to specific proline-containing targets, improving the overall efficacy and reducing side effects of the treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 37888-34-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,8,8 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 37888-34:
(7*3)+(6*7)+(5*8)+(4*8)+(3*8)+(2*3)+(1*4)=169
169 % 10 = 9
So 37888-34-9 is a valid CAS Registry Number.

37888-34-9Relevant academic research and scientific papers

Stereoselective Synthesis of Desmethoxy-(+)-verruculogen TR-2

Boyd, Steven A.,Thompson, Wayne J.

, p. 1790 - 1794 (1987)

An efficient five-step stereoselective synthesis of (+)-desmethoxyverruculogen TR-2 from L-tryptophan is presented.

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