37904-84-0

Usage

Uses

Used in Chemical Synthesis:
2,6-Diphenylcyclohexanone is used as a starting material for the synthesis of complex organic compounds, such as cisand trans-2-(p-carboxybenzyl)-2,6-diphenyl-6-vinylcyclohexanone. Its unique structural properties make it a valuable component in the creation of these compounds, which can have various applications in different industries.
Used in Photochemical Applications:
The cis-isomer of 2,6-diphenylcyclohexanone is used in photochemical applications due to its photochemical activity. It undergoes photodecarbonylation reactions, which can be harnessed for various purposes, such as the development of new materials or the modification of existing ones.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, 2,6-diphenylcyclohexanone and its derivatives could potentially be used in the pharmaceutical industry for the development of new drugs or drug delivery systems, given their structural diversity and synthetic utility.
Used in Research and Development:
2,6-Diphenylcyclohexanone and its related compounds can be used in research and development settings to explore new chemical reactions, mechanisms, and applications. The study of its photochemical properties and synthetic potential can lead to the discovery of novel compounds and technologies.

InChI:InChI=1/C18H18O/c19-18-16(14-8-3-1-4-9-14)12-7-13-17(18)15-10-5-2-6-11-15/h1-6,8-11,16-17H,7,12-13H2

Upstream product

• 109-64-8 1,3-dibromo-propane 
• 102-04-5 1,3-Diphenylpropanone 
• 108-94-1 cyclohexanone 
• 108-90-7 chlorobenzene 
• 74456-85-2 N-((2R,6R)-2,6-Diphenyl-cyclohexylidene)-N'-phenyl-hydrazine 
• 1444-65-1 (RS)-2-phenylcyclohexanone 
• 1201786-60-8 6-bromo-1,2,3,4-tetrahydro-1,1'-biphenyl 
• 1542147-98-7 (S)-1-(1,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)ethanone 
• 1542147-92-1 (S)-6-bromo-1,2,3,4-tetrahydro-1,1'-biphenyl 
• 1542147-96-5 C₁₄H₁₈O 
• 83324-28-1 Phenyl-(6-phenyl-cyclohex-1-enyl)-diazene 
• 108-86-1 bromobenzene 

Downstream Products

• 20834-02-0 cis-2,6-diphenylcyclohexanone 

Relevant academic research and scientific papers

Synthesis of trans -2,6-disubstituted cyclohexanones through allylic substitution

trans-2,6-Disubstituted cyclohexanones were synthesized with high regio- and stereoselectivity by allylic substitution followed by ozonolysis. Both alkyl and aryl groups were successfully installed to the cyclohexane ring. The stereochemistry of the Ssub

Suzuki-Miyaura, α-ketone arylation and dehalogenation reactions catalyzed by a versatile N-heterocyclic carbene-palladacycle complex

The activity of the complex (IPr)PdCl(η2-N,C-C 12H7NMe2), 1 [IPr = (N,N′-bis(2,6- diisopropylphenyl)-imidazol)-2-ylidene], in the Suzuki-Miyaura cross-coupling reaction involving unactivated aryl chlorides and triflates with arylboronic acids at room temperature in technical grade 2-propanol is described. These conditions allow for the synthesis of di- and tri-ortho-substituted biaryls in very short reaction times. This complex also displays very high activity for α-ketone arylation and dehalogenation reactions of activated and unactivated aryl chlorides.

Reactions of the Lithium Salts of the Tribenzylidenemethane Dianion, Diphenylacetone Dianion, and Related Compounds

Potentially synthetically useful reactions of the dilithium salts of the title dianions have been investigated. Electrophilic quenching with a variety of reagents usually leads to the expected products in good yield. Quenching the diphenylacetone dianion with 1 equiv of trimethylchlorosilane, however, gives a good yield of 1,3-diphenylallene obtained by formal elimination of a trimethylsiloxy anion from an intermediate monoquenched monoanion salt. NMR studies, however, do not reveal the intermediacy of the 1,3-diphenyl-2-(trimethylsiloxy)allyl anion but rather suggest that the initial reaction site is at carbon, rather than oxygen. Oxidation of the dianions leads either to ring closure or dimerization for the tribenzylidenemethane dianion and to dimerization for the diphenylacetone dianion. The dimerization reactions are stereospecific, both with respect to the two new stereocenters produced and for the double bonds of the bis-silyl enol ether products if the dimeric bis-enolate dianion products are quenched with trimethylchlorosilane.

Reactions of Cojugated Arylazocycloalkenes with Grignard Reagents. Part 3. A Convenient Synthesis of 2,6-Diaryl- and 2-Alkyl-6-aryl-cyclohexanones

A synthesis of the title compounds with the substituents at C-2 and C-6 trans to each other is described. 2-Arylcyclohexanones were converted into 1-phenylazo-6-arylcyclohexenes, which by reaction with Grignard reagents led to trans-2,6-diaryl- and trans-