3792-02-7

Usage

Uses

Used in Pharmaceutical Industry:
5,5,6,6,7,7,8,8,8-NONAFLUOROOCTAN-1-OL is used as a surfactant, emulsifier, and wetting agent for the formulation of pharmaceutical products. Its properties allow for improved solubility, stability, and bioavailability of drugs.
Used in Textile Industry:
In the textile industry, 5,5,6,6,7,7,8,8,8-NONAFLUOROOCTAN-1-OL is used as a surfactant and wetting agent to enhance the dyeing and finishing processes. Its ability to lower surface tension helps improve the wetting and spreading of dyes on fabric surfaces.
Used in Electronics Industry:
5,5,6,6,7,7,8,8,8-NONAFLUOROOCTAN-1-OL is used as a surfactant and wetting agent in the electronics industry for the manufacturing of printed circuit boards and other electronic components. Its stability and resistance to heat and chemicals make it suitable for use in harsh manufacturing environments.
Used as a Lubricant:
5,5,6,6,7,7,8,8,8-NONAFLUOROOCTAN-1-OL is used as a lubricant in various applications due to its low friction coefficient and resistance to wear. Its stability and inertness make it suitable for use in high-temperature and chemically aggressive environments.
Used in the Production of Fluorinated Polymers:
5,5,6,6,7,7,8,8,8-NONAFLUOROOCTAN-1-OL is used as a component in the production of fluorinated polymers, which have a wide range of applications in various industries, including aerospace, automotive, and medical.
It is important to handle 5,5,6,6,7,7,8,8,8-NONAFLUOROOCTAN-1-OL with care as it may have potential health and environmental risks.

InChI:InChI=1/C8H9F9O/c9-5(10,3-1-2-4-18)6(11,12)7(13,14)8(15,16)17/h18H,1-4H2

Upstream product

• 27854-33-7 5,5,6,6,7,7,8,8,8-Nonafluoro-octanoic acid 
• 627-27-0 homoalylic alcohol 
• 423-39-2 1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane 
• 109574-81-4 5,5,6,6,7,7,8,8,8-nonafluoro-3-iodooctan-1-ol 
• 36389-98-7 diethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)malonate 
• 36390-03-1 2-<2-(Perfluorbutyl)-ethyl>-malonsaeure 
• 2043-55-2 3,3,4,4,5,5,6,6,6-nonafluorohexyliodide 

Downstream Products

• 162082-63-5 4-(perfluorobutyl)butyl p-toluenesulfonate 
• 38436-18-9 8-bromo-1,1,1,2,2,3,3,4,4-nonafluoro-octane 

Relevant academic research and scientific papers

Effect of the fluorination degree of partially fluorinated octyl-phosphocholine surfactants on their interfacial properties and interactions with purple membrane as a membrane protein model

Interfacial properties and membrane protein solubilization activity of a series of partially fluorinated octyl-phosphocholine (PC) surfactants were investigated from the viewpoint of the fluorination degree of the hydrophobic chain. The critical micelle concentration (CMC), surface tension lowering activity, molecular occupied area at the CMC and free energy changes of micellization as well as adsorption to the air-water interface for each PC surfactant were estimated from surface tension measurements at 25 °C. The PCs with higher degree of fluorination exhibited low CMC and high surface activity, while the single trifluoromethyl group at the end of the chain appeared to enhance the hydrophilicity of the surfactant molecule. Under conditions where conventional short-chain surfactants, n-octyl-β-D-glucoside, Triton X-100 and dioctanoylphosphatidylcholine significantly solubilize purple membranes (PM), none of the fluorinated-PCs solubilized PM. This suggests that fluorinated-PCs are low-invasive enough to maintain the structure of lipids/protein assemblies like PM.

COMPOUNDS USEFUL IN HIV THERAPY

The invention relates to compounds of Formula (I), salts thereof, pharmaceutical compositions thereof, as well as methods of treating or preventing HIV in subjects.

METHOD FOR PREPARING FLUORINATED BENZOTRIAZOLE COMPOUNDS

Fluorinated benzotriazole compounds may be prepared by contacting a fluorochemical monofunctional compound, such a fluorinated alcohol, with a carboxybenzotriazole in the presence of a coupling agent, and an optional amine catalyst.

BRANCHED-TYPE SURFACTANT HAVING BOTH FLUOROALKYL AND HYDROCARBON GROUPS

PROBLEM TO BE SOLVED: To provide a surfactant usable in a carbon dioxide-water system. SOLUTION: The surfactant is represented by general formula(I)[ wherein, Rf is an (ether linkage-bearing) fluoroalkyl; Rh is an alkyl; X1 and X2 are each a bivalent linkage group; p is 0 or 1; q is 0 or 1; n is an integer of 1-10; and M is H, an alkali metal atom, 1/2 alkaline earth metal atom or ammonium group ].

FLUORINATED PHOSPHONIC ACIDS

Fluorinated phosphonic acid compounds, useful as treatments for substrate surfaces, have the formula (I) : wherein: R?1? is a straight chain alkylene group having from 3 to 21 carbon atoms, an oxa-substituted straight chain alkylene group having from 2 to 20 carbon atoms, or a thia-substituted straight chain alkylene group having from 2 to 20 carbon atoms; R?2? is a perfluoroalkyl group having from 4 to 10 carbon atoms; R?3? is hydrogen, an alkali metal cation, or an alkyl group having from 1 to 6 carbon atoms; and M is hydrogen or an alkali metal cation, with the proviso that if R?1? is an unsubstituted straight chain alkylene group, then the sum of carbon atoms in R?1? and R?2? combined is at least 10.

3-methyl-chroman and -thiochroman derivatives

The present invention provides a compound having the following general formula (1): in which R1represents a hydrogen atom, etc.; R2represents a C3-C3perhalogenoalkyl group, etc.; each of R3and R4independently represents a hydrogen atom, etc.; X represents an oxygen atom or a sulfur atom; m represents an integer of 2 to 14; and n represents an integer of 0 to 8; or enantiomers of the compound, or hydrates or pharmaceutically acceptable salts of the compound or its enantiomers. The compound of general formula (1) is advantageous in pharmaceutical use because of its anti-estrogenic activity.

Convenient synthesis of thiols and disulfides in the polyfluorinated series incorporating a butylic spacer

New fluorinated thiols R(F)(CH2)(p)SH and disulfides [R(F)(CH2)(p)S]2 containing a butylic spacer (p=4) between the perfluorinated part and the thiol (or disulfide) function were easily obtained in good yields with a purity higher than 98%. This allows us to obtain homologues (p>4) for their use as synthetic intermediates or as constituents for molecular organized systems. (C) 2000 Elsevier Science Ltd.