37933-78-1

Basic information

• Product Name: L-lysine o-acetoxybenzoate
• Synonyms: L-lysine o-acetoxybenzoate;acetylsalicylic acid lysinate;L-Lysine/2-acetyloxybenzoic acid,(1:x);Aspirin lysinate;Einecs 253-723-0;Solusprin
• CAS NO: 37933-78-1
• Molecular Formula: C15H22N2O6
• Molecular Weight: 326.34498
• EINECS: 253-723-0
• Mol File: 37933-78-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 321.4°Cat760mmHg
• Flash Point: 131.2°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.000124mmHg at 25°C
• CAS DataBase Reference: L-lysine o-acetoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: L-lysine o-acetoxybenzoate(37933-78-1)
• EPA Substance Registry System: L-lysine o-acetoxybenzoate(37933-78-1)

Safety Data

• Hazardous Substances Data: 37933-78-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H8O4.C6H14N2O2/c1-6(10)13-8-5-3-2-4-7(8)9(11)12;7-4-2-1-3-5(8)6(9)10/h2-5H,1H3,(H,11,12);5H,1-4,7-8H2,(H,9,10)/t;5-/m.0/s1

Upstream product

• 70-54-2 2,6-diaminocaproic acid 
• 50-78-2 aspirin 
• 56-87-1 L-lysine 

Relevant articles and documents

IMPROVED SYNTHESIS OF LYSINE ACETYLSALICYLATE · GLYCINE PARTICLES

The invention relates to a method for the production of acetylsalicylic acid lysinate, optionally lysine acetylsalicylate · glycine, comprising the following steps: a) providing a solution of acetylsalicylic acid in ethanol; b) providing an aqueous solution of lysine; c) combining the solutions of step a) and b) to form a mixture; d) optionally stirring the mixture; e) adding acetone to the mixture; f) incubating the mixture, to allow the formation of a acetylsalicylic acid lysinate product; g) isolating the acetylsalicylic acid lysinate product; wherein acetylsalicylic acid is used in excess compared to lysine and wherein no seed crystals are added to the mixture; and optionally the following further steps: h) providing a recrystallized glycine; wherein the glycine has been recrystallized with the following steps: h1) dissolving glycine in water; h2) adding acetone to the glycine solution; h3) stirring the mixture until a precipitate is obtained; i) combining the recrystallized glycine of step h) with the acetylsalicylic acid lysinate product of step g) to obtain lysine acetylsalicylate · glycine (LASAG) particles.

Interactions of acetylsalicyclic acid and lysine in solution

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