37941-27-8

Basic information

• Product Name: 4-Pyridinamine, N,N-dimethyl-2-phenyl-
• CAS NO: 37941-27-8
• Molecular Formula: C13H14N2
• Molecular Weight: 198.268
• Mol File: 37941-27-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 4-Pyridinamine, N,N-dimethyl-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinamine, N,N-dimethyl-2-phenyl-(37941-27-8)
• EPA Substance Registry System: 4-Pyridinamine, N,N-dimethyl-2-phenyl-(37941-27-8)

Safety Data

• Hazardous Substances Data: 37941-27-8(Hazardous Substances Data)

Upstream product

• 57311-18-9 4-chloro-2-phenyl-pyridine 
• 506-59-2 N,N-dimethylammonium chloride 
• 396092-82-3 2-bromo-4-(N,N-dimethylamino)pyridine 
• 396092-83-4 (2-iodo-pyridin-4-yl)-dimethyl-amine 
• 98-80-6 phenylboronic acid 
• 17945-94-7 3-phenyl-1-azabicyclo[1.1.0]butane 
• 816-65-9 N-(1-ethoxyvinyl)-N,N-dimethylamine 
• 591238-50-5 3-phenyl-2-azabuta-1,3-diene 
• 18162-28-2 5-phenyl-1,2,4-triazine 
• 124-40-3 dimethyl amine 
• 626-61-9 4-Chloropyridine 

Relevant articles and documents

Red to blue emitting cationic iridium complexes with 2-phenyl-4-dimethylaminopyridine as the cyclometalating ligand: Synthesis, characterization and electroluminescent devices

2-Phenyl-4-dimethylaminopyridine (dmappy) with high 3π-π? triplet energy is, for the first time, employed as the cyclometalating ligand for constructing cationic iridium complexes with tunable emission properties. Three complexes, na

C6-Selective Direct Arylation of 2-Phenylpyridine via an Activated N-methylpyridinium Salt: A Combined Experimental and Theoretical Study

An elegant pre-activation strategy, based on the formation of N-methylpyridinium iodide salts for C6-selective direct arylation of 2-phenylpyridines using Pd/Cu cooperative catalysis, has been developed. By this methodology, a wide range of unsymmetrical 2, 6-diarylpyridines were synthesized with high reactivity and regioselectivity as well as good functional group tolerance. In particular, challenging substrates bearing electron donating groups (EDGs), such as OMe, NMe2, were also successfully employed in this reaction. Deuterium incorporation studies revealed that the C?H bond acidity is improved significantly in N-methylpyridinium salts compared with their N-Oxide and N-iminopyridinium ylide counterparts, thus solving the long-standing problem associated with previous strategies for the synthesis of diaryl pyridines. Finally, the control experiments and DFT calculations supported a Pd-catalyzed and Cu-mediated mechanism in which a carbenoid copper species that is formed in-situ from N-methylpyridinium salts, participates in a Pd-catalyzed arylation followed by an iodide-promoted N-demethylation process. (Figure presented.).

Iron-catalyzed direct arylation through directed C-H bond activation

An iron-catalyzed C-C bond formation reaction of a nitrogen-containing aromatic compound with an arylzinc reagent takes place at 0 °C in a good to quantitative yield. The reaction involves a C-H bond activation directed by a neighboring nitrogen atom. The important additives in this reaction are 1,10-phenanthroline, tetramethylethylenediamine, and 1,2-dichloro-2-methylpropane, in the absence of which a very low product yield was observed. Copyright