396092-83-4

Usage

Uses

Used in Organic Synthesis:
2-Iodo-4-dimethylaminopyridine is used as a catalyst for promoting various organic reactions, including esterifications, amidations, and alkylations. Its ability to efficiently catalyze these reactions makes it a valuable tool in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2-Iodo-4-dimethylaminopyridine is utilized for the synthesis of various active pharmaceutical ingredients. Its role in facilitating key chemical reactions contributes to the development of new and improved medications, thereby enhancing the scope of available treatments for various health conditions.

InChI:InChI=1/C7H9IN2/c1-10(2)6-3-4-9-7(8)5-6/h3-5H,1-2H3

Upstream product

• 83674-71-9 2,4-diiodo-pyridine 
• 124-40-3 dimethyl amine 
• 26452-80-2 2,4-dichloropyridine 
• 1122-58-3 dmap 

Downstream Products

• 918682-01-6 2-(3-methoxyphenyl)-4-dimethylaminopyridine 
• 37941-27-8 N,N-dimethyl-2-phenylpyridin-4-amine 
• 441072-26-0 2-(2,4-difluorophenyl)-4-N,N-dimethylaminopyridine 
• 918681-86-4 2-(3,5-difluorophenyl)-4-dimethylaminopyridine 
• 1017276-53-7 C₂₃H₂₈N₂O₅ 
• 1189463-00-0 2-(2,4-dichlorophenyl)-N,N-4-dimethylaminopyridin 
• 1416450-11-7 N²,N²'-((1R,2R)-cyclohexane-1,2-diyl)bis(N⁴,N⁴-dimethylpyridine-2,4-diamine) 
• 1421748-76-6 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2R)-2-((4-(dimethylamino)pyridin-2-yl)amino)cyclohexyl)thiourea 
• 1421748-66-4 C₁₄H₂₄N₄O₂S 
• 1421748-67-5 C₁₄H₂₁F₃N₄O₂S 
• 1421748-68-6 C₂₀H₂₈N₄O₂S 
• 1421748-69-7 C₂₂H₃₂N₄O₂S 
• 1421748-70-0 C₂₈H₄₄N₄O₂S 
• 1421748-71-1 C₂₂H₃₁N₅O₄S 

Relevant academic research and scientific papers

Design of an Os Complex-Modified Hydrogel with Optimized Redox Potential for Biosensors and Biofuel Cells

Multistep synthesis and electrochemical characterization of an Os complex-modified redox hydrogel exhibiting a redox potential ≈+30 mV (vs. Ag/AgCl 3 m KCl) is demonstrated. The careful selection of bipyridine-based ligands bearing N,N-dimethylamino moieties and an amino-linker for the covalent attachment to the polymer backbone ensures the formation of a stable redox polymer with an envisaged redox potential close to 0 V. Most importantly, the formation of an octahedral N6-coordination sphere around the Os central atoms provides improved stability concomitantly with the low formal potential, a low reorganization energy during the Os3+/2+ redox conversion and a negligible impact on oxygen reduction. By wiring a variety of enzymes such as pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase, flavin adenine dinucleotide (FAD)-dependent glucose dehydrogenase and the FAD-dependent dehydrogenase domain of cellobiose dehydrogenase, low-potential glucose biosensors could be obtained with negligible co-oxidation of common interfering compounds such as uric acid or ascorbic acid. In combination with a bilirubin oxidase-based biocathode, enzymatic biofuel cells with open-circuit voltages of up to 0.54 V were obtained.

NOVEL COMPOUNDS

This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, Ar, R1, R2, R3 have meanings given in the description.

SUBSTITUTED TRIAZOLES AND THEIR USE FOR TREATMENT AND/OR PREVENTION NEUROLOGICAL AND PSYCHIATRIC DISORDERS

This invention relates to compounds of formula (I), their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, Ar, R1, R2, R3 have meanings given in the description.

Selective and multiple functionalization of pyridines and alkaloids via Mg- and Zn-organometallic intermediates

Chemical equations presented. Quinine, nicotine, and related electron-rich amino-substituted pyridines were readily metalated using LiCl-solubilized TMP (2,2,6,6-tetramethylpiperidyl) bases in the presence of BF3· OEt2. A full pyridi

Light-Emitting Material

This invention pertains to light emitting materials comprising novel ortho-metalated transition metal complexes [C?N]2ML, comprising chelate monoionic ligands (L), also called ancillary ligands. It has been surprisingly found that when the ancillary ligand comprises a substituted aromatic ring bearing a substituent possessing adequate electron-donating properties, said ligand (L) advantageously participates in the emission process, significantly shifting emission towards higher energies (blue-shift) and enabling appreciable improvement of the emission efficiency of complexes [C?N]2ML. Still objects of the invention are the use of said light emitting materials and organic light emitting device comprising said light emitting material.

LIGHT EMITTING MATERIAL

This invention pertains to light emitting materials comprising novel ortho-metalated transition metal complexes [C^N]2M[P^O] comprising two orthometalated chelate C^N ligands and an ancillary ligand of bidentate phosphinocarboxylate type. It ha

Sequence dependence of methylation rate enhancement in meta- phenyleneethynylene foldamers

The methylation rates of a meta-phenyleneethynylene (mPE) oligomer with a terminally-attached 4-dimethylaminopyridine (DMAP) residue are reported for a series of linear and branched methyl sulfonates; these data show that selective methylation is enhanced

ELECTRO LUMINESCENT METAL COMPLEXES

Electro luminescent metal, e.g. Ir, complexes are disclosed. The metal complexes comprise at least one ligand Ll and at least one ligand L2, wherein ligand Ll is a 2-phenylpyridine ligand (I), comprising a phenyl ring (A) and a pyridine ring (B). The inte

Light-emitting material

This invention pertains to light emitting materials comprising novel ortho-metalated transition metal complexes [C^N]2M(T)(L), comprising chelate C^N ligands, monodentate neutral ligand (L) having sp2 hybridized N atom and a monodent