37951-15-8Relevant academic research and scientific papers
PROCESS FOR THE PREPARATION OF ROXADUSTAT AND ITS INTERMEDIATES
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Page/Page column 28-29, (2019/06/17)
The present invention provides the process for the preparation of Roxadustat and its intermediates. Another aspect of the present invention provides a process for preparation of ethyl-5-(2-butoxycarbonyl)-4-phenoxyphenyl) oxazole-4-carboxylate of the formula (X) and its use in the preparation of Roxadustat. Another aspect of the present invention provides a process for the preparation of ethyl-4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate of the formula (XIII) and its use in the preparation of Roxadustat.
Lipophilic N-Hydroxyphthalimide Catalysts for the Aerobic Oxidation of Cumene: Towards Solvent-Free Conditions and Back
Petroselli, Manuel,Melone, Lucio,Cametti, Massimo,Punta, Carlo
, p. 10616 - 10625 (2017/08/09)
A new class of lipophilic N-hydroxyphthalimide (NHPI) catalysts designed for the aerobic oxidation of cumene in solvent-free conditions was synthesized and tested. The specific strategy proposed for the introduction of lipophilic tails on the NHPI moiety
CRYSTAL TYPES OF COMPOUNDS INHIBITING ACTIVITY OF PROLYL HYDROXYLASE AND USE THEREOF
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, (2017/10/27)
The invention relates to crystal types of compound shown as structural formula I, methods of preparing the compound, intermediate, pharmaceutical composition, and use of treating disease or pharmaceutical preparations for treating disease.
POLYMORPHIC FORMS OF COMPOUNDS AS PROLYL HYDROXYLASE INHIBITOR, AND USES THEREOF
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, (2015/02/19)
The present invention relates to the polymorphic forms of the compound of Formula (I), preparation thereof including the preparation of intermediates and pharmaceutical compositions, and use of a polymorph above in the treatment of a disease, a disorder o
POLYMORPHIC FORMS OF COMPOUNDS AS PROLYL HYDROXYLASE INHIBITOR, AND USES THEREOF
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, (2013/03/26)
The present invention relates to the polymorphic forms of the compound of Formula (I), preparation thereof including the preparation of intermediates and pharmaceutical compositions, and use of a polymorph above in the treatment of a disease, a disorder o
Novel nitrogen-containing heteroaryl compounds and methods of use thereof
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Page 42, (2008/06/13)
The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo.
