379693-45-5Relevant academic research and scientific papers
The Mitsunobu reaction in the synthesis of α,α-difluoro-β-amino acids
Fokina, Natalie A.,Kornilov, Andrei M.,Kukhar, Valery P.
, p. 69 - 76 (2001)
A three-stage strategy is proposed to prepare α,α-difluoro-β-amino acids starting from aldehydes and with ethyl bromodifluoroacetate as a fluorine source. The Mitsunobu reaction as a key step was studied by 31P and 19F NMR for alkyl-
