38009-92-6

Upstream product

• 64-17-5 ethanol 
• 861524-26-7 2-benzenesulfonyl-2,2-dichloro-1-phenyl-ethanone 
• 873-55-2 sodium benzenesulfonate 
• 38042-52-3 2-chloro-2-(phenylsulfinyl)-1-phenyl-1-ethanone 
• 93-58-3 benzoic acid methyl ester 
• 7205-98-3 chloromethyl phenyl sulfone 
• 28322-50-1 2-diazo-1-phenyl-2-(phenylsulfonyl)ethan-1-one 
• 70-11-1 α-bromoacetophenone 
• 16222-10-9 1-phenyl-2-(phenylthio)ethanone 
• 3406-03-9 2-(phenylsulfonyl)acetophenone 

Downstream Products

• 3406-03-9 2-(phenylsulfonyl)acetophenone 
• 77006-49-6 2-Benzenesulfonyl-3-phenyl-5,6-dihydro-imidazo[2,1-b]thiazole 
• 195371-23-4 p-Tolyl-chlorbrommethyl-sulfon 
• 40230-56-6 2-chloro-1-phenyl-2-(phenylsulfonyl)ethan-1-ol 
• 861524-26-7 2-benzenesulfonyl-2,2-dichloro-1-phenyl-ethanone 
• 7205-98-3 chloromethyl phenyl sulfone 
• 925901-22-0 2-benzenesulfonyl-2-bromo-2-chloro-1-phenyl-ethanone 

Relevant academic research and scientific papers

Copper Triflate Mediated α-Monohalogenation of α-Diazo β-Ketosulfones with Ammonium Halides

Copper triflate mediated α-monohalogenation of α-diazo β-ketosulfones with ammonium halides provides the corresponding α-halo β-ketosulfones. Different metal triflates are investigated for this facile and efficient transformation. A plausible mechanism is proposed.

Synthesis of fluorinated β-ketosulfones and gem-disulfones by nucleophilic fluoroalkylation of esters and sulfinates with di- and monofluoromethyl sulfones

(Chemical Equation Presented) An efficient and practically useful method for the preparation of α-functionalized mono- and difluoro(phenylsulfonyl) methanes by using a nucleophilic fluoroalkylation methodology was developed. α,α-Difluoro-β-ketosulfones, α

Chemoselective mono halogenation of β-keto-sulfones using potassium halide and hydrogen peroxide; synthesis of halomethyl sulfones and dihalomethyl sulfones

The synthesis of α-halo β-keto-sulfones using potassium halide and hydrogen peroxide as a chemoselective mono halogenation reagent and the synthesis of α,α-symmetrical and asymmetrical dihalo β-keto-sulfones and α-halo, α-alkyl and β-keto-sulfones is described. Base induced cleavage of α-halo β-keto-sulfones, α,α-dihalo β-keto-sulfones, and α-halo, α-alkyl β-keto-sulfones afforded the corresponding halomethyl sulfones, dihalomethyl sulfones and haloalkyl sulfones.

Mild Halogenation of Stabilized Ester Enolates by Cupric Halides

The reactions of various stabilized ester enolates of 2-keto, 2-(alkoxycarbonyl), 2-phosphoryl, and 2-(benzenesulfonyl) esters with cupric chloride or cupric bromide have been examined.The reactions lead to 2-halo esters in good to excellent yields under mild condition.Enolates which contain an unsaturated functionality such as a double bond, a triple bond, or an allylic or a benzylic moiety react with high chemoselectivity.

Effect of Structural Change on Acute Toxicity and Antiinflammatory Activity in a Series of Imidazothiazoles and Thiazolobenzimidazoles

The effect of structural change on the biological activity of a series of imidazothiazoles and thiazolobenzimidazoles is described.It was found that compounds with polar substituents at the 2 or 3 position of the ring system are less acutely toxic while maintaining antiinflammatory activity.Other structural changes, such as the incorporation of a gem-dimethyl substituent in the 6 position, increase acute toxicity and eliminate antiinflammatory activity.The compound with the best activity/toxicity ratio contains an alkyl sulfonyl substituent on the thiazole ring.The thiazolobenzimidazole analogues are more potent than the imidazole analogues.