38010-31-0

Upstream product

• 3406-03-9 2-(phenylsulfonyl)acetophenone 
• 873-55-2 sodium benzenesulfonate 
• 587-65-5 N-chloroacetyl-aniline 
• 108-86-1 bromobenzene 
• 35008-50-5 2-(phenylsulphonyl)-acetamide 
• 62-53-3 aniline 
• 515-42-4 sodium phenylsulfonate 
• 5326-87-4 N-(phenyl)bromoacetamide 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 62-53-3 aniline 
• 38010-17-2 2-Benzenesulfonyl-2-[(2-ethoxy-phenyl)-hydrazono]-N-phenyl-acetamide 
• 38010-29-6 2-{N'-[1-Benzenesulfonyl-1-phenylcarbamoyl-meth-(E)-ylidene]-hydrazino}-benzoic acid 
• 38010-18-3 2-Benzenesulfonyl-2-[(2-hydroxy-phenyl)-hydrazono]-N-phenyl-acetamide 
• 38010-16-1 2-Benzenesulfonyl-2-[(2-methoxy-phenyl)-hydrazono]-N-phenyl-acetamide 
• 38010-15-0 2-Benzenesulfonyl-2-[(3-methoxy-phenyl)-hydrazono]-N-phenyl-acetamide 
• 38010-26-3 2-Benzenesulfonyl-2-[(2-nitro-phenyl)-hydrazono]-N-phenyl-acetamide 
• 38010-27-4 2-Benzenesulfonyl-2-[(3-nitro-phenyl)-hydrazono]-N-phenyl-acetamide 
• 38010-28-5 4-{N'-[1-Benzenesulfonyl-1-phenylcarbamoyl-meth-(E)-ylidene]-hydrazino}-benzoic acid 
• 38010-20-7 2-Benzenesulfonyl-N-phenyl-2-(o-tolyl-hydrazono)-acetamide 
• 38010-21-8 2-Benzenesulfonyl-N-phenyl-2-(m-tolyl-hydrazono)-acetamide 
• 38010-23-0 Benzolsulfonylglyoxylanilid-p-chlorphenylhydrazon 
• 38010-14-9 2-Benzenesulfonyl-2-[(4-methoxy-phenyl)-hydrazono]-N-phenyl-acetamide 
• 38010-19-4 2-Benzenesulfonyl-N-phenyl-2-(p-tolyl-hydrazono)-acetamide 

Relevant academic research and scientific papers

One-pot copper-catalyzed three-component reaction: A modular approach to functionalized 2-quinolones

A copper-catalyzed three-component annulation for the synthesis of functionalized 2-quinolones was developed. Three reactions including an SN2, a Knoevenagel, and finally C-N bond formation are involved in the designed cascade reaction using 2-bromoacylarenes, 2-iodoacetamide, and nucleophiles as the three components. A new catalytic system was discovered during the study and this modular approach is highly efficient to access functionalized 2-quinolone derivatives, compatible with a broad range of functional groups, scalable, and step-economic. Further derivatization of the obtained product demonstrates the synthetic utility of this method.

Reaction of different α-sulfonyl acetamides with methyl acrylate

The base-induced tandem-coupling/cyclization reactions of various α-sulfonyl acetamide derivatives A with methyl acrylate differentiated between two different pathways to form α-sulfonyl analogs of glutarimides B and 2-hydroxycyclohexenecarboxylic acid derivatives C in different ratios. The reaction of α-sulfonyl acetamide dianion with methyl acrylate depended on three factors: the stability of the dianion, concentration of methyl acrylate and the structure of sufonyl and amide substituents. By changing the reaction conditions, we efficiently controlled the cycloaddition reaction to synthesize the desired product, each of which has potential biological activities. A ring closure mechanism is proposed for the reactions.

α-Phenylsulfonyl-N-arylacetamides (α-phenylsulfonylacetanilides): 1H, 13C and 15N NMR spectral characterization

1H and 13C NMR chemical shift assignments for 11 α-phenylsulfonylacetanilides and 15N NMR chemical shifts for four representative congeners are reported. The 1H and 13C chemical shift assignments are based on DQF COSY and PFG 1H, 13C HMQC/HMBC experiments. The 15N NMR chemical shifts were determined by PFG 1H, 15N HMBC experiments. The correlation analyses with Hammett-type substituent constants gave a significant result with δ(C-1) in the aniline ring. Copyright

A Novel Synthesis of Sulfones via the O,O-Diethylphosphorotellurite Ion-Assisted Coupling of Arenesulfonyl Chlorides with Active Halides

Arenesulfonyl chlorides undergo a facile onepot coupling reaction with active halides assisted by sodium O,O-diethylphosphorotellurite to give the corresponding sulfones in excellent yield.