35008-50-5Relevant articles and documents
Benzenesulfonamide compounds
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Paragraph 0103; 0113-0115, (2021/04/20)
The present invention provides a benzenesulfonamide compound represented by chemical formula 1 or a biotinylated compound thereof. The compounds of the present invention selectively react with a sulfhydryl group (-SH) having unoxidized cysteine, and do no
Selective ruthenium-catalyzed hydration of nitriles to amides in pure aqueous medium under neutral conditions
Cadierno, Victorio,Francos, Javier,Gimeno, Jose
scheme or table, p. 6601 - 6605 (2009/07/10)
A study was conducted to demonstrate that water-soluble ruthenium(II) complexes can be used as catalysts for the hydration of nitriles in pure aqueous media and under neutral conditions. The hydration of benzonitrile was investigated as a model reaction and the ruthenium precursor was added to a 0.33M aqueous solution of benzonitrile at 100°C, while the reaction was monitored by gas chromatography. All the complexes checked, were found to be active and selective catalysts in the hydration process, providing benzamide as a specific reaction product. The most relevant results were obtained by using ruthenium complexes, bearing a nitrogen-containing ligand, which led to appropriate production of benzamide. The most effective ruthenium complex was found to be an efficient catalyst for the selective hydration of a large number of other nitriles.
Efficient lactam synthesis
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, (2008/06/13)
Lactams, libraries of lactams, and an efficient method of synthesizing a lactam, including a γ-lactam, in which an a-diazoacetamide of the general structure (I) is reacted under conditions promoting intramolecular C-H insertion, for example in the presenc
