38046-82-1

Basic information

• Product Name: 4-FLUOROBENZYLMAGNESIUM CHLORIDE 0.25M&
• Synonyms: 6-Methoxy-2-naphthylmagnesium bromide solution 0.5 in THF;6-Methoxy-2-naphthylmagnesium bromide, 0.5M solution in THF, AcroSeal;6-Methoxy-2-naphthylMagnesiuM broMide, 0.5M in THF;6-Methoxy-2-naphthylMagnesiuM broMide, 0.5 M solution in THF, SpcSeal;6-Methoxy-2-naphthylmagnesium bromide solution 0.5 M in THF;magnesium,6-methoxy-2H-naphthalen-2-ide,bromide;4-FLUOROBENZYLMAGNESIUM CHLORIDE 0.25M&;6-METHOXY-2-NAPHTHYLMAGNESIUM BROMIDE, 0.5 M SOLUTION IN THF
• CAS NO: 38046-82-1
• Molecular Formula: C₁₁H₉BrMgO
• Molecular Weight: 261.4
• Product Categories: Aryl;Grignard Reagents;Organometallic Reagents
• Mol File: 38046-82-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 35 °C
• Flash Point: -13 °F
• Appearance: /
• Density: 0.966 g/mL at 25 °C
• Vapor Pressure: 0.0104mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-FLUOROBENZYLMAGNESIUM CHLORIDE 0.25M&(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FLUOROBENZYLMAGNESIUM CHLORIDE 0.25M&(38046-82-1)
• EPA Substance Registry System: 4-FLUOROBENZYLMAGNESIUM CHLORIDE 0.25M&(38046-82-1)

Safety Data

• Hazard Codes: F+,C,F,Xn
• Statements: 12-14-19-22-34-67-11-40-36/37
• Safety Statements: 9-16-29-33-45-36/37-26
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 1
• Hazardous Substances Data: 38046-82-1(Hazardous Substances Data)

Usage

General Description

4-FLUOROBENZYLMAGNESIjson CHLORIDE 0.25M is a chemical compound that consists of a 0.25M solution of 4-Fluorobenzylmagnesium chloride. 4-FLUOROBENZYLMAGNESIUM CHLORIDE 0.25M& is commonly used in organic synthesis as a mild and selective nucleophile for the formation of carbon-carbon and carbon-heteroatom bonds. It is often utilized in Grignard reactions to introduce the 4-Fluorobenzyl group into organic molecules, and it can also serve as a valuable reagent for the preparation of pharmaceutical intermediates and fine chemicals. The 0.25M concentration indicates the molarity of the solution, which is a measure of the number of moles of the compound dissolved in one liter of solvent. Overall, 4-FLUOROBENZYLMAGNESIUM CHLORIDE 0.25M is an important reagent in organic chemistry with applications in various synthetic processes.

InChI:InChI=1/C11H9O.BrH.Mg/c1-12-11-7-6-9-4-2-3-5-10(9)8-11;;/h3-8H,1H3;1H;/q-1;;+2/p-1

Upstream product

• 5111-65-9 2-Bromo-6-methoxynaphthalene 

Downstream Products

• 71964-75-5 2-(6-methoxy-2-naphthoyl)benzoic acid 
• 60533-05-3 3-(6-methoxy-[2]naphthyl)-2,2-dimethyl-pent-3-enoic acid 
• 102018-88-2 2-acetoxy-3-(6-methoxy-[2]naphthyl)-cyclohex-2-enone 
• 3453-33-6 6-methoxynaphthalene-2-carbaldehyde 
• 2700-47-2 6-methoxy-2-propionylnaphthalene 
• 123871-53-4 2-methoxy-6-(E)-styrylnaphthalene 
• 2471-70-7 2-methoxy-6-naphthoic acid 
• 31220-35-6 (R,S) naproxen ethyl ester 
• 1248350-26-6 (R,E)-2-methoxy-6-(4-phenylbut-3-en-2-yl)naphthalene 
• 1248350-27-7 (S)-(-)-1-phenyl-3-(6-methoxy-2-naphthyl)-1-butene 
• 1065544-58-2 [2-(1-benzyl-1H-indol-3-yl)phenyl](6-methoxynaphthalen-2-yl)methanol 

Relevant articles and documents

Naphthylene derivatives as cytochrome P450 inhibitors

Compounds of the formula and pharmaceutically acceptable salts thereof, wherein n1, n2, n3, n4, G1, Q1, Z, R1, R2, R3, R4a, R4b, R5a, and R5b are defined he

Optically active 1-(6-methoxy-2-naphthyl)-2-(alkoxycarbonyl) amino-1-propanone, its derivatives and their halo analogs and the methods for their manufacture

A manufacturing method is described for the preparation of optically active 1-(6-methoxy-2-naphthyl)-2-(alkoxycarbonyl)amino-1-propanone, its derivatives and their halo analogs. The optically active 1-(6-methoxy-2-naphthyl)-2-(alkoxycarbonyl)amino-1-propanone, its derivatives and their halo analogs are useful intermediates in the preparation of 2-(6-methoxy-2-naphthyl)propionic acid, which is useful as pharmaceutical, e.g. antiinflammatory, analgesic and anti-pyretic agents.