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1-(chloromethyl)-4-[2-[4-(chloromethyl)phenyl]ethyl]benzene, also known as Chloroethylbenzene, is a chlorinated aromatic compound with the molecular formula C16H17Cl2. It is a colorless, flammable liquid characterized by a strong, sweet odor and is soluble in organic solvents. Due to its potential to cause respiratory and skin irritation, as well as its environmental toxicity, it is classified as a hazardous substance. Additionally, it is considered a possible carcinogen, necessitating proper safety precautions during handling and use.

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  • 38058-86-5 Structure
  • Basic information

    1. Product Name: 1-(chloromethyl)-4-[2-[4-(chloromethyl)phenyl]ethyl]benzene
    2. Synonyms:
    3. CAS NO:38058-86-5
    4. Molecular Formula: C16H16Cl2
    5. Molecular Weight: 279.209
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 38058-86-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 383.7°Cat760mmHg
    3. Flash Point: 198.4°C
    4. Appearance: N/A
    5. Density: 1.171g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-(chloromethyl)-4-[2-[4-(chloromethyl)phenyl]ethyl]benzene(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-(chloromethyl)-4-[2-[4-(chloromethyl)phenyl]ethyl]benzene(38058-86-5)
    11. EPA Substance Registry System: 1-(chloromethyl)-4-[2-[4-(chloromethyl)phenyl]ethyl]benzene(38058-86-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 38058-86-5(Hazardous Substances Data)

38058-86-5 Usage

Uses

Used in Chemical Synthesis:
1-(chloromethyl)-4-[2-[4-(chloromethyl)phenyl]ethyl]benzene is used as a reagent in organic synthesis for the production of various organic chemicals. Its chloromethyl groups facilitate a range of chemical reactions, making it a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Manufacturing Industry:
In the manufacturing industry, 1-(chloromethyl)-4-[2-[4-(chloromethyl)phenyl]ethyl]benzene is utilized as a key intermediate in the production of various organic chemicals. Its unique structure allows for the creation of a wide array of compounds with diverse applications, contributing to the development of new materials and products.
Used in Research and Development:
1-(chloromethyl)-4-[2-[4-(chloromethyl)phenyl]ethyl]benzene is also employed in research and development settings, where its properties are studied and harnessed to create novel compounds and materials. Its potential applications in various fields, including pharmaceuticals and materials science, make it an important compound for scientific exploration and innovation.

Check Digit Verification of cas no

The CAS Registry Mumber 38058-86-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,0,5 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 38058-86:
(7*3)+(6*8)+(5*0)+(4*5)+(3*8)+(2*8)+(1*6)=135
135 % 10 = 5
So 38058-86-5 is a valid CAS Registry Number.

38058-86-5Relevant articles and documents

EPIDITHIODIKETOPIPERAZINE COMPOUNDS, COMPOSITIONS, AND METHODS

-

, (2015/07/07)

Epidithiodiketopiperazine compounds, pharmaceutical compositions based thereon and methods of their synthesis, as part of treating, inhibiting and reducing transcription and translation of hypoxia inducible genes are described. In another aspect, the present disclosure describes a method for interfering with hypoxia-induced transcriptional pathway in a cell comprising: contacting the cell with at least one compound disclosed herein. In another aspect, the present disclosure describes a method for treating breast cancer, a solid cancer, a blood cancer, a subject suffering from carcinoma in need of said treatment, and renal cell carcinoma (RCC), comprising: administering to the subject an effective amount of at least one compound disclosed herein. In some embodiments of the methods described herein, the method further comprises administering an additional anti-cancer and/or cytotoxic agent.

Synthesis and structure-activity analysis of new phosphonium salts with potent activity against African trypanosomes

Taladriz, Andrea,Healy, Alan,Flores Pérez, Eddysson J.,Herrero García, Vanessa,Ríos Martínez, Carlos,Alkhaldi, Abdulsalam A. M.,Eze, Anthonius A.,Kaiser, Marcel,De Koning, Harry P.,Chana, Antonio,Dardonville, Christophe

, p. 2606 - 2622 (2012/06/01)

A series of 73 bisphosphonium salts and 10 monophosphonium salt derivatives were synthesized and tested in vitro against several wild type and resistant lines of Trypanosoma brucei (T. b. rhodesiense STIB900, T. b. brucei strain 427, TbAT1-KO, and TbB48). More than half of the compounds tested showed a submicromolar EC50 against these parasites. The compounds did not display any cross-resistance to existing diamidine therapies, such as pentamidine. In most cases, the compounds displayed a good selectivity index versus human cell lines. None of the known T. b. brucei drug transporters were required for trypanocidal activity, although some of the bisphosphonium compounds inhibited the low affinity pentamidine transporter. It was found that phosphonium drugs act slowly to clear a trypanosome population but that only a short exposure time is needed for irreversible damage to the cells. A comparative molecular field analysis model (CoMFA) was generated to gain insights into the SAR of this class of compounds, identifying key features for trypanocidal activity.

The 4,4′-(1,2-ethanediyl)bisbenzyl biradical: Its generation, detection, and (photo)chemical behavior in solution

Miranda,Font-Sanchis,Perez-Prieto,Scaiano

, p. 2717 - 2721 (2007/10/03)

The 4,4′-(1,2-ethanediyl)bisbenzyl biradical (2) is clearly and efficiently generated by photolysis of [3.2]paracyclophane-2-one (8) in cyclohexane solution. This intermediate is also formed via two-photon processes from [2.2]paracyclophane (3) and 1,2-bi

Reductive Coupling by Chromium(0) - (Bibenzyl)- and (Stilbene)tricarbonylchromium(0) Complexes by a One-Pot Reaction from Benzylic Halides

Wey, Hans G.,Butenschoen, Holger

, p. 93 - 99 (2007/10/02)

Reaction of Cr(CO)3(NH3)3 with benzylic mono-, di-, and trihalides leads to the formation of 1,2-diarylethanes, -ethenes, and diphenylethyne in satisfactory yields.Di(halomethyl)benzene derivatives yield product mixtures containing both reduction products and coupling products.With a higher excess in chromium(0), under otherwise unchanged reaction conditions, the corresponding (arene)tricarbonylchromium(0) complexes of the coupling products are formed in a one-pot reaction from the benzylic halides.

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