38063-81-9

Basic information

• Product Name: 4-AMINOACETOPHENONE OXIME
• Synonyms: 4'-AMINOACETOPHENONE OXIME;4-AMINOACETOPHENONE OXIME;1-(4-aminophenyl)ethan-1-one oxime;Ethanone, 1-(4-aminophenyl)-, oxime (9CI);1-(4-Aminophenyl)ethanone oxime;Nsc77944
• CAS NO: 38063-81-9
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• Product Categories: OXIME;Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes
• Mol File: 38063-81-9.mol
• Article Data: 18

Chemical Properties

• Melting Point: 153
• Boiling Point: 323.5°C at 760 mmHg
• Flash Point: 149.5°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 0.000107mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: 4-AMINOACETOPHENONE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINOACETOPHENONE OXIME(38063-81-9)
• EPA Substance Registry System: 4-AMINOACETOPHENONE OXIME(38063-81-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 38063-81-9(Hazardous Substances Data)

Usage

General Description

4-Aminoacetophenone oxime is a chemical compound with the molecular formula C8H9N2O. It is an oxime derivative of 4-aminoacetophenone, and it is used in the synthesis of various organic compounds and pharmaceuticals. This chemical is a white to light yellow crystalline solid, and it is soluble in water and organic solvents. 4-Aminoacetophenone oxime is commonly used in organic synthesis as a building block for the preparation of heterocyclic compounds and as a reagent for the determination of various metal ions in solution. It also has pharmaceutical applications, particularly in the development of drugs for the treatment of various diseases. Overall, 4-Aminoacetophenone oxime is an important chemical with versatile applications in research and industry.

InChI:InChI=1/C8H10N2O/c1-6(10-11)7-2-4-8(9)5-3-7/h2-5,11H,9H2,1H3/b10-6+

Upstream product

• 10342-64-0 p-nitroacetophenone oxime 
• 99-92-3 p-aminobenzophenone 

Downstream Products

• 38063-87-5 1-(4-amino-phenyl)-ethanone O-(2-morpholin-4-yl-ethyl)-oxime 
• 38063-88-6 2-[1-(4-amino-phenyl)-ethylideneaminooxy]-N-(2-morpholin-4-yl-ethyl)-N-phenyl-acetamide 
• 92103-10-1 5'-Chlor-2',4'-dinitro-4-acetyl-diphenylamin-oxim 
• 1208365-98-3 C₁₇H₂₀N₄O₂ 
• 1260236-30-3 N-(1-(4-acetamidophenyl)vinyl)acetamide 
• 1129278-89-2 1-(p-aminophenyl)ethylamine hydrochloride 
• 122-80-5 N-acetyl-p-phenylenediamine 
• 1597446-27-9 (Z)-4-({4-[1-(hydroxyimino)ethyl]phenylimino}(phenyl)methyl)-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one 
• 1446947-62-1 1-(4-{[(E)-3,5-dibromo-2-hydroxybenzylidene]amino}-phenyl)ethanone oxime 
• 75270-71-2 p-salicyliden-p-aminoacetophenone oxime 
• 1202385-74-7 4-amino-3-iodoacetophenone oxime 
• 99-92-3 p-aminobenzophenone 
• 75270-68-7 (C₄H₉)3SnONC(CH₃)C₆H₄NH₂-4 
• 69365-69-1 3,4,5-trimethoxy-N-{4-[1-(2-morpholin-4-yl-ethoxyimino)-ethyl]-phenyl}-benzamide 

Relevant articles and documents

Beckmann rearrangement of ketoximes promoted by cyanuric chloride and dimethyl sulfoxide under a mild condition

Synthesis of amides via Beckmann rearrangement of ketoximes promoted by cyanuric chloride (TCT)/DMSO under mild conditions has been reported. Conditions of the Beckmann rearrangement, e.g., solvents, the ratios of TCT/DMSO, and the temperature, were investigated using diphenylmethanone oxime as a substrate. The optimized conditions were adopted to afford fourteen amides with yields ranging from 20% to 99%. A plausible mechanism involving an active dimethyl alkoxysulfonium intermediate was proposed according to the mass spectrometry analysis. To our best knowledge, this is the first case of study on Beckmann rearrangement of ketoximes promoted by TCT/DMSO under a mild condition to afford amides efficiently.

Method for preparing aromatic amine compounds from aromatic nitro compounds by catalytic reduction of nano porous gold catalyst

The invention discloses a method for preparing aromatic amine compounds from aromatic nitro compounds by catalytic reduction of a nano porous gold catalyst. The nano porous gold catalyst and the aromatic nitro compounds are taken as substrates and subjected to a reaction in methanol with ammonia borane as a hydrogen source at the room temperature, and a product is obtained. The high probability ofagglomeration of conventional granular catalysts is prevented, the nano porous gold catalyst shows excellent structural stability and good recycling efficiency, has excellent universality, especiallyfor the aromatic nitro compounds, and has green and mild catalytic conditions, high yield and good selectivity. The yield of m-nitroaniline from m-nitrotoluene can reach 98%. Moreover, the catalyst can be centrifugally recovered and can be recycled without other treatment, the yield of preparing m-nitroaniline from m-nitrotoluene by catalyzing can still reach 88% after being recycled five times,and thus, waste is effectively avoided. The catalyst shows high activity during the reaction and excellent stability under the reaction conditions.

Copper-Catalyzed Three-Component Domino Cyclization for the Synthesis of 4-Aryl-5-(arythio)-2-(trifluoromethyl)oxazoles

A copper-catalyzed oxidative cyclization of oxime, arylthiol, and trifluoroacetic anhydride for the construction of trisubstituted oxazoles has been developed. This transformation combines N-O bond cleavage, C-H functionalization, and intramolecular annulation, providing a practical protocol for the introduction of a trifluoromethyl (-CF3) group at oxazole rings.