38107-62-9Relevant academic research and scientific papers
Palladium-Catalyzed Amination of C-5 Bromoimidazo[2,1-b][1,3,4]thiadiazoles
Copin, Chloé,Buron, Frédéric,Routier, Sylvain
, p. 1958 - 1962 (2016)
A new and efficient palladium-catalyzed amination of imidazo[2,1-b][1,3,4]thiadiazole at the C-5 position under microwave irradiation is reported. The reactivity toward bromine release at the C-5 position was investigated, and palladium-catalyzed cross-co
Synthesis of 2,6-disubstituted imidazo[2,1-b][1,3,4]thiadiazoles through cyclization and Suzuki-Miyaura cross-coupling reactions
Copin, Chloe,Henry, Nicolas,Buron, Frederic,Routier, Sylvain
supporting information; experimental part, p. 3079 - 3083 (2012/07/01)
Highly substituted imidazo[2,1-b][1,3,4]thiadiazole derivatives were synthesized through successive cyclization and Suzuki-Miyaura cross-coupling reactions. The palladium-catalyzed coupling reaction was optimized and a wide range of boronic acids was used to evaluate the scope and limitations of the methodology. The final compounds were obtained in fair to very good yields and high compatibility with various chemical functions or (hetero)cycles was observed. Copyright
Synthesis and cardiotonic activity of certain imidazo[2,1-b]-1,3,4-thiadiazole derivatives
El-Sherbeny,El-Bendary,El-Subbagh,El-Kashef
, p. 253 - 256 (2007/10/03)
A series of 5-imino-2-methyl-4-(4'-substituted phenacyl)-1,3,4-thiadiazole derivatives 3-5 have been synthesized and furtherly used to prepare a series of 2-methyl-6-(4'-substituted phenyl)imidazo[2,1-b]-1,3,4-thiadiazoles 6-8 and 5-substituted-2-methyl-6
