3815-86-9 Usage
Description
Malonic dihydrazide, also known as 1,3-dihydrazinane-1,3-bis(methoxycarbonyl)propane, is a white crystalline solid with the molecular formula C5H12N4O4. It is a chemical compound primarily used as a crosslinking agent in polymer chemistry, known for its ability to form stable complexes with metal ions. This makes it useful in various applications such as chelation therapy and metal ion sensing. Additionally, it serves as a precursor in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, making it a valuable building block in organic synthesis and materials science. However, it is important to handle malonic dihydrazide with care, as it is a potential irritant to the skin, eyes, and respiratory system.
Uses
Used in Polymer Chemistry:
Malonic dihydrazide is used as a crosslinking agent for enhancing the properties of polymers, such as their stability and mechanical strength.
Used in Chelation Therapy:
Malonic dihydrazide is used as a chelating agent for the treatment of heavy metal poisoning, as it can form stable complexes with metal ions, aiding in their removal from the body.
Used in Metal Ion Sensing:
Malonic dihydrazide is used as a sensing agent for detecting and quantifying metal ions in various environments, due to its ability to form stable complexes with these ions.
Used in Pharmaceutical Synthesis:
Malonic dihydrazide is used as a precursor in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and therapies.
Used in Agrochemical Synthesis:
Malonic dihydrazide is used as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides, to improve crop protection and yield.
Used in Organic Synthesis and Materials Science:
Malonic dihydrazide is used as a versatile building block in organic synthesis and materials science, enabling the creation of new compounds and materials with unique properties.
Check Digit Verification of cas no
The CAS Registry Mumber 3815-86-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,1 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3815-86:
(6*3)+(5*8)+(4*1)+(3*5)+(2*8)+(1*6)=99
99 % 10 = 9
So 3815-86-9 is a valid CAS Registry Number.
InChI:InChI=1/C3H8N4O2/c4-6-2(8)1-3(9)7-5/h1,4-5H2,(H,6,8)(H,7,9)
3815-86-9Relevant articles and documents
The reaction of ethyl 2-oxo-2H-chromene-3-carboxylate with hydrazine hydrate
Abdel-Aziz, Hatem A.,Elsaman, Tilal,Attia, Mohamed I.,Alanazi, Amer M.
, p. 2084 - 2095 (2013/04/23)
Although salicylaldehyde azine (3) was reported in 1985 as the single product of the reaction of ethyl 2-oxo-2H-chromene-3-carboxylate (1) with hydrazine hydrate, we identified another main reaction product, besides 3, which was identified as malono-hydrazide (4). In the last two decades, however, some articles have claimed that this reaction afforded exclusively hydrazide 2 and they have reported the use of this hydrazide 2 as a precursor in the syntheses of several heterocyclic compounds and hydrazones 6. We reported herein a study of the formation of 2 and a facile route for the synthesis of the target compounds N'-arylidene-2-oxo-2H-chromene-3-carbohydrazides 6a-f.
Efficient synthesis of 4-ethoxycarbonyl pyrazolin-5-one derivatives
Jung, Jae C.,Watkins, E Blake,Avery, Mitchell A.
, p. 3767 - 3777 (2007/10/03)
Concise and efficient methods for the preparation of 3-substituted 4-ethoxycarbonylpyrazolin-5-ones are described. The synthetic strategies involve carbon-acylation in the presence of base, followed by ring cyclization with hydrazine or hydrazine monohydrochloride.
