38175-73-4

Upstream product

• 33491-05-3 1-(2-bromoethynyl)-4-methylbenzene 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 766-97-2 4-n-methylphenylacetylene 
• 583-53-9 2,3-dibromobenzene 
• 624-31-7 4-tolyl iodide 
• 766-46-1 2-bromo-1-ethynylbenzene 
• 583-55-1 1-Bromo-2-iodobenzene 

Downstream Products

• 955024-69-8 triisopropyl(2-(p-tolylethynyl)phenylthio)silane 
• 141240-85-9 1,1-Diphenyl-2-p-tolyl-1H-benzo[b]silole 
• 1021176-07-7 2-[(4-methylphenyl)ethynyl]-4'-(trifluoromethyl)biphenyl 
• 1021176-10-2 3',5'-difluoro-2-[(4-methylphenyl)ethynyl]biphenyl 
• 1021176-14-6 2-[(4-methylphenyl)ethynyl]-3',5'-bis(trifluoromethyl)biphenyl 
• 1021176-37-3 2-[(4-methylphenyl)ethynyl]-biphenyl-d5 
• 1021176-38-4 2-(phenylethynyl)-biphenyl-d1 
• 1021176-09-9 5-fluoro-2-methyl-2'-[(4-methylphenyl)ethynyl]biphenyl 
• 1045601-72-6 allyldimethyl{2-[(4-methylphenyl)ethynyl]phenyl}silane 
• 1239896-04-8 2-tert-butyl-N-(2-(p-tolylethynyl)phenyl)aniline 
• 25664-47-5 2-(4-methylphenyl)benzo[b]thiophene 
• 1363267-91-7 1,1-dimethyl-8-phenyl-3-(p-tolyl)-2-tosyl-1,2-dihydroindeno[1,2-c]pyrrole 
• 1021176-17-9 C₂₂H₁₇F 
• 1192052-55-3 C₂₁H₁₅Cl 

Relevant academic research and scientific papers

Diaryl acetylene compound containing methylene quinone as well as preparation method and application of diaryl acetylene compound

The invention discloses a diaryl acetylene compound containing methylene quinone as well as a preparation method and application thereof, and belongs to the technical field of pharmacy and chemical industry. The structural formula of the diarylacetylene c

Metal-Free Aminoiodination of Alkynes Under Visible Light Irradiation for the Construction of a Nitrogen-Containing Eight-Membered Ring System

A method for the synthesis of dihydrodibenzo[c,e]azocine derivatives via a regioselective intramolecular aminoiodination of alkynes under visible light irradiation has been developed. This protocol uses a combination of iodine and hypervalent iodine to re

Gold-Catalyzed Cascade and Divergent Synthesis of Indolobenzazepines and Indoloquinolines from Nitrogen-Tethered 1,8-Diynes

We describe the divergent construction of two nitrogen-containing polycyclic systems by gold-catalyzed cycloisomerizations. The gold-catalyzed cascade hydroamination and 7-endo-dig-selective cycloisomerization of nitrogen-tethered 1,8-diynes yielded indol

Sequential Addition of Amines to Nitrile and Carbon-Carbon Multiple Bond: A Route to 7-Amino-5 H-dibenzo[ c,e]azepines

A rare earth metal-catalyzed sequential inter- and intramolecular C-N bond formation of 2-nitrile-2′-alkenyl(alkynyl)biphenyls with amines has been developed, which provides a straightforward and efficient access to a range of new functional dibenzo[c,e]azepines. This represents the first examples of direct construction of seven-membered azaheterocycle from unsaturated nitriles and amines. Such transformations have the advantages of avoiding the use of additives, easily available starting materials, step- and high atom-economy, mild reaction conditions, and high selectivity.

Concise synthesis of phospholene and its P-stereogenic derivatives

A simple method to build phospholene derivatives has been achieved in a one-pot reaction with readily available o-alkynylaryl bromides and alkylphosphine oxides. This method is also applicable to synthesize P-stereogenic phospholenes, and the resulting chiral phosphine was utilized as a ligand for coordination chemistry.

Trithiocarbonate Anion as a Sulfur Source for the Synthesis of 2,5-Disubstituted Thiophenes and 2-Substituted Benzo[ b]thiophenes

The trithiocarbonate anion (CS32-) was generated in situ from CS2 and KOH in dimethyl sulfoxide by a simple method and used as a novel synthetic equivalent of the S2- synthon for the synthesis of 2,5-disubstituted thiophenes from 1,3-butadiynes. Additionally, this system was employed for the metal-free synthesis of 2-substituted benzo[b]thiophenes from 2-haloalkynyl (hetero)arenes. These compounds were obtained from a cheap and readily available sulfur source in moderate to good yields, with good functional group tolerance.

Enantioselective Synthesis of 1-Aryl Benzo[5]helicenes Using BINOL-Derived Cationic Phosphonites as Ancillary Ligands

The synthesis of unprecedented BINOL-derived cationic phosphonites is described. Through the use of these phosphanes as ancillary ligands in AuI catalysis, a highly regio- and enantioselective assembly of appropriately designed alkynes into 1-(

Domino Palladium-Catalyzed Double Norbornene Insertion/Annulation Reaction: Expeditious Synthesis of Overcrowded Tetrasubstituted Olefins

A Pd-catalyzed domino process involving a double norbornene insertion/annulation reaction was developed for the expeditious synthesis of overcrowded olefins. In this one-pot reaction, four new C-C bond formations were achieved by three consecutive Heck ca

Synthesis of divergent benzo[b]fluorenones through cycloaromatization reactions of 1,5-enynols and 1,5-diynols

A facile and efficient synthesis of divergent benzo[b]fluorenones is described through the use of dichlorobenzoquinone-promoted oxidative cycloaromatization reactions of acyclic 1,5-enynols and 1,5-diynols. The success of these cascade reactions depends on the chemoselectivity of the initial Meyer-Schuster rearrangement to produce allenol intermediate, which is followed by regioselective Schmittel cyclization and the subsequent Friedal-Crafts alkylation or radical attack at the terminal Ar moiety. Only an oxidant and a solvent were required in the reaction, thus delivering a small library of the expected polycarbocyclic products with excellent functional group tolerance under metal-free conditions. The absorption and photoluminescence properties of the selected benzo[b] fluorenones were also investigated. The results indicated that the compound (2h) which contained an electron-donating 4-OMe group at the phenyl moiety displayed deep green color emission (491 nm).

Synthesis of Naphthalenyl Triflates via the Cationic Annulation of Benzodiynes with Triflic Acid

A highly efficient and regioselective annulation of benzodiynes promoted by triflic acid has been developed. This protocol provides a step and atom-economic access to a series of naphthalenyl triflates. Furthermore, direct synthetic applications of this r