38177-98-9

Basic information

• Product Name: Ethanone, 1-(4-amino-2-methylphenyl)- (9CI)
• Synonyms: Ethanone, 1-(4-amino-2-methylphenyl)- (9CI);1-(4-Amino-2-methyl-phenyl)-ethanone;4-Amino-2-methylacetophenone;Ethanone, 1-(4-aMino-2-Methylphenyl)-
• CAS NO: 38177-98-9
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.18974
• Product Categories: ACETYLGROUP
• Mol File: 38177-98-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 305.8 °C at 760 mmHg
• Flash Point: 138.7 °C
• Appearance: /
• Density: 1.067 g/cm³
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Ethanone, 1-(4-amino-2-methylphenyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-amino-2-methylphenyl)- (9CI)(38177-98-9)
• EPA Substance Registry System: Ethanone, 1-(4-amino-2-methylphenyl)- (9CI)(38177-98-9)

Safety Data

• Hazardous Substances Data: 38177-98-9(Hazardous Substances Data)

Usage

Uses

4-Amino-2-methylacetophenone is a useful reagent in the preparation of some polycyclic systems with multiple commercial applications.

Upstream product

• 537-92-8 3-Methylacetanilide 
• 75-36-5 acetyl chloride 
• 108-44-1 1-amino-3-methylbenzene 
• 34956-31-5 N-(4-acetyl-3-methylphenyl)acetamide 

Downstream Products

• 23600-94-4 (Acetyl-4-methyl-3-phenyl)-phenyl-amin 
• 23689-03-4 (Acetyl-4-methyl-3-phenyl)-(carboxyl-2'-phenyl)-amin 
• 69450-94-8 4-ethyl-3-methylaniline 

Relevant articles and documents

Doxepin analogs and methods of use thereof

The invention relates to novel antihistamines and methods of modulating sleep by administering a doxepin analog or a pharmaceutically effective salt thereof.

Modification of Photochemical Reactivity by Cyclodextrin Complexation: Product Selectivity in Photo-Fries Rearrangement

Cyclodextrin encapsulation, both in the solid state and in aqueous solution brings about a remarkable regulation of the photo-Fries rearrangement of phenyl esters and anilides.In comparison to the non-selective mixture of ortho and para-rearranged isomers along with the deacylated product obtained in organic solvents, the solid β-cyclodextrin complexes of unsubstituted esters and anilides show a remarkable 'ortho-selectivity'.An impressive 'regio-selectivity' among the two ortho-rearranged isomers is observed for meta-substituted esters and anilides upon irradiation as β-cyclodextrin complexes.Specific orientations of the unsubstituted and meta-substituted esters and anilides in the β-cyclodextrin cavity are suggested to be responsible for the observed selectivity.