38185-19-2

Basic information

• Product Name: 4-(METHYLTHIO)BENZYL BROMIDE 97
• Synonyms: 4-(METHYLTHIO)BENZYL BROMIDE 97;4-(broMoMethyl)phenyl Methyl sulfide;(4-(broMoMethyl)phenyl)(Methyl)sulfane;4-(Methylthio)benzyl broMide 97%;1-(bromomethyl)-4-(methylthio)benzene;QDLKMRTVELBKFE-UHFFFAOYSA-N
• CAS NO: 38185-19-2
• Molecular Formula: C₈H₉BrS
• Molecular Weight: 217.129
• Product Categories: Organic Building Blocks;Sulfides/Disulfides;Sulfur Compounds
• Mol File: 38185-19-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 43-47 °C(lit.)
• Boiling Point: 274.5°C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.44g/cm³
• Vapor Pressure: 0.00902mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 4-(METHYLTHIO)BENZYL BROMIDE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(METHYLTHIO)BENZYL BROMIDE 97(38185-19-2)
• EPA Substance Registry System: 4-(METHYLTHIO)BENZYL BROMIDE 97(38185-19-2)

Safety Data

• Hazard Codes: C
• Statements: 34-43
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 2923 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 38185-19-2(Hazardous Substances Data)

Usage

Uses

4-(Methylthio)benzyl bromide can undergo self-catalyzed oxidation in the presence of hydrogen peroxide to form the corresponding sulfoxide.

InChI:InChI=1/C8H9BrS/c1-10-8-4-2-7(6-9)3-5-8/h2-5H,6H2,1H3

Upstream product

• 3446-89-7 4-(Methylthio)benzaldehyde 
• 558-13-4 carbon tetrabromide 
• 3446-90-0 4-(methylthio)benzyl alcohol 
• 3795-79-7 methyl 4-(methylthio)benzoate 
• 13205-48-6 4-(methylthio)benzoic acid 

Downstream Products

• 112460-37-4 β-aspartic acid p-(methylthio)benzyl ester 
• 112460-38-5 γ-glutamic acid p-(methylthio)benzyl ester 
• 3446-89-7 4-(Methylthio)benzaldehyde 
• 216989-23-0 3-(4-isopropylphenyl)-2,2,4,6,7-pentamethyl-5-(4-methylthiobenzyloxy)-2,3-dihydrobenzofuran 
• 3446-90-0 4-(methylthio)benzyl alcohol 
• 51927-46-9 1-bromomethyl-4-methanesulfinylbenzene 
• 1191098-88-0 N-[2-[4-(methylthio)phenyl]-1-phenylethyl]aniline 
• 1252671-01-4 3,3-bis(4-(methylthio)benzyl)-1-tosylpyrrolidin-2-one 
• 1304038-87-6 C₈₄H₃₀OS 
• 1255907-89-1 bis(4-methylthiobenzyl)diselenide 
• 1255907-83-5 4-methylthiobenzylselenocyanate 
• 1337551-83-3 methyl(4-(3-phenylprop-2-ynyl)phenyl)sulfane 
• 1337927-69-1 4'-(thiomethyl)phenylnitromethane 
• 1337927-63-5 (E)-1-[4'-(methylthio)phenyl]-1-nitro-2-phenylethene 

Relevant articles and documents

Synthetic Strategy for Tetraphenyl-Substituted All-E-Carotenoids with Improved Molecular Properties

The synthetic method of tetraphenyl-substituted all-E-carotenes 1 with improved properties of antioxidant and molecular electronic conductance was developed through the formation of tetraphenyl-substituted all-E-apocarotenedial 4. The synthesis highlighted the preparation of novel subunits containing phenyl substituent(s) with E-configuration starting from the key (E)-4-chloro-2-phenylbut-2-enal (10), utilizing conjugation effect with formyl group or easy recrystallization of sulfone compounds. Sulfone-mediated coupling methods of Julia and modified Julia–Kocienski olefinations utilizing the subunits were demonstrated to produce tetraphenyl-substituted apocarotenedials 4. The major all-E-forms (73–85 % selectivity) were easily purified by SiO2 chromatography and trituration with Et2O due to the presence of the polar formyl groups. The olefination of all-E-apocarotenedials 4 and Wittig salt 5 provided all-E-9,9',13,13'-tetraphenylcarotenes 1.

Anthranilic acid derivatives as inhibitors of the cGMP-phosphodiesterase

Compounds of formula (I) STR1where R 1 is hydrogen; R 2 is nitro, cyano or halo(lower)alkyl; R 3 is phenyl substituted with one or more substituents selected from halogen, cyano and lower alkoxy; A is a lower alkylene group; R 4 is a group CR 6 R 7 R 8 wherein R 6 and R 7 form, together with the carbon atom to which they are attached a cycloalkyl group optionally substituted with hydroxy, lower alkoxy or a lower alkanoylamino; and R 8 is hydrogen; its prodrug and a salt thereof.