38196-02-0

Usage

InChI:InChI=1/C15H11NO3/c17-14(18)9-10-6-7-13-12(8-10)16-15(19-13)11-4-2-1-3-5-11/h1-8H,9H2,(H,17,18)

Upstream product

• 10463-20-4 4-hydroxy-3-nitrophenylacetic acid 
• 56350-37-9 2-phenyl-5-benzoxazolylcarboxaldehyde cyanohydrin 
• 7440-44-0 pyrographite 
• 51234-49-2 (2-phenyl-benzooxazol-5-yl)-acetonitrile 
• 5333-86-8 ethyl benzimidate hydrochloride 
• 38196-08-6 4-hydroxy-3-amino-phenylacetic acid 
• 143-33-9 sodium cyanide 
• 54785-43-2 5-bromomethyl-2-phenyl-benzooxazole 

Downstream Products

• 1026725-80-3 N-[5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-hydroxy-phenyl]-2-(2-phenyl-benzooxazol-5-yl)-acetamide 

Relevant academic research and scientific papers

2-Phenyl-5-benzoxazolylalkanoic acid purification process

Crude preparations of 2-phenyl-5-benzoxazolylalkanoic acids are purified by forming the ammonium salt thereof in an organic solvent and thermally reconverting the separated ammonium salt to the acid. Gaseous ammonia is a by-product.

2-(Optionally substituted)phenyl-5 or 6-substituted benzoxazoles

2-(Optionally substituted)phenyl-benzoxazoles having a carboxy alkyl, a tetrazolyl, or oxazolinyl group at the 5 or 6 position useful as aspirin-like non-steroidal, non-narcotic, analgesic, antipyretic and anti-inflammatory agents.

2,5 OR 2,6 Disubstituted benzoxazoles

5- or 6-Substituted benzoxazole propionic or acetic acid derivatives, substituted in the 2-position of the oxazole nucleus by a group of the formula AR4 wherein A is --CH2 --, --CO--, --CHOR--, or --NR--, wherein R is hydrogen, Csub

Benzoxazole derivatives in treating inflammation, pain and fever

The invention provides novel 5- and 6-benzoxazolyl alkanoic acids, optionally substituted in the 2-position, and derivatives thereof which possess anti-inflammatory, anti-pyretic and analgesic activity. Also provided is a process for preparing such compounds by cyclising an appropriately substituted o-aminophenol and, if necessary, converting the resultant benzoxazole to the desired compound.