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Benzene, 1-chloro-2-[(trifluoromethyl)sulfonyl]-, also known as 1-Chloro-2-(trifluoromethylsulfonyl)benzene, is an organic compound with the chemical formula C7H4ClF3O2S. It is a colorless liquid with a molecular weight of 254.61 g/mol. Benzene, 1-chloro-2-[(trifluoromethyl)sulfonyl]- is characterized by the presence of a benzene ring, with a chlorine atom at the 1-position and a trifluoromethylsulfonyl group at the 2-position. The trifluoromethylsulfonyl group is a strong electron-withdrawing group, which makes Benzene, 1-chloro-2-[(trifluoromethyl)sulfonyl]- a valuable intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its reactivity and potential applications, it is essential to handle Benzene, 1-chloro-2-[(trifluoromethyl)sulfonyl]- with care, following proper safety protocols and guidelines.

382-70-7

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382-70-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 382-70-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,8 and 2 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 382-70:
(5*3)+(4*8)+(3*2)+(2*7)+(1*0)=67
67 % 10 = 7
So 382-70-7 is a valid CAS Registry Number.

382-70-7Relevant academic research and scientific papers

Practical and efficient synthesis of aryl trifluoromethyl sulfones from arylsulfonyl chlorides with Umemoto's reagent II

Zhou, Xiaocong,Hu, Dufen,He, Xinyi,Li, Yuanqiang,Chu, Youqun,She, Yuanbin

supporting information, (2019/12/24)

A practical and efficient method for the synthesis of aryl trifluoromethyl sulfones has been developed by a tandem reaction of arylsulfonyl chlorides with Umemoto's reagent II. The advantageous features of this method are simple operation, mild reaction conditions, wide scope of substrates, high yield of products, and easy scalability.

PREPARATION AND FLUORINATION OF ARYLTRIFLUOROMETHYLSULPHONES

Beaumont, Andrew J.,Clark, James H.

, p. 295 - 300 (2007/10/02)

A series of chloro- and nitrophenyl trifluoromethyl sulphides and sulphones have been synthesised from the corresponding aryl halides .The fluorination of these compounds by tetra-n-butyl ammonium fluoride and potassium fluoride has been investigated.Our results show that generally they are more susceptible to fluorodenitration than fluorodechlorination.

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