382137-74-8 Usage
Uses
Used in Molecular Recognition Applications:
6-METHYL-3-(BETA-D-2-DEOXYFURANOSYL)PYRROLO[2,3-D]PYRIMIDIN-2-ONE is used as a key component in the development of pyrrolo-dC based fluorescent aptasensors. These aptasensors are designed for highly specific molecular recognition of various targets, such as proteins, nucleic acids, and small molecules, making them valuable tools in research, diagnostics, and therapeutics.
Used in Diagnostics Industry:
In the diagnostics industry, 6-METHYL-3-(BETA-D-2-DEOXYFURANOSYL)PYRROLO[2,3-D]PYRIMIDIN-2-ONE is used as a building block for the development of novel diagnostic tools. 6-METHYL-3-(BETA-D-2-DEOXYFURANOSYL)PYRROLO[2,3-D]PYRIMIDIN-2-ONE's ability to form specific interactions with target molecules allows for the creation of highly sensitive and selective detection systems, which can be applied in the early detection and monitoring of various diseases and conditions.
Used in Research and Development:
6-METHYL-3-(BETA-D-2-DEOXYFURANOSYL)PYRROLO[2,3-D]PYRIMIDIN-2-ONE is also used in research and development for the creation of new chemical entities and materials with potential applications in various fields, such as pharmaceuticals, biotechnology, and materials science. 6-METHYL-3-(BETA-D-2-DEOXYFURANOSYL)PYRROLO[2,3-D]PYRIMIDIN-2-ONE's unique structure and properties make it an attractive candidate for the design and synthesis of novel molecules with specific functions and activities.
Check Digit Verification of cas no
The CAS Registry Mumber 382137-74-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,2,1,3 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 382137-74:
(8*3)+(7*8)+(6*2)+(5*1)+(4*3)+(3*7)+(2*7)+(1*4)=148
148 % 10 = 8
So 382137-74-8 is a valid CAS Registry Number.
382137-74-8Relevant academic research and scientific papers
Loakes, David,Brown, Daniel M.,Salisbury, Stephen A.,McDougall, Mark G.,Neagu, Constantin,Nampalli, Satyam,Kumar, Shiv
, p. 1193 - 1204 (2003)
A novel nucleoside analogue is described based on the pyridazine ring system. The nucleoside was successfully incorporated into DNA via both its phosphoramidite and 5′-triphosphate derivatives. Enzymatically, the analogue behaves essentially as thymidine:
Pyrrolo-dC and pyrrolo-C: Fluorescent analogs of cytidine and 2′-deoxycytidine for the study of oligonucleotides
Berry, David A.,Jung, Kee-Yong,Wise, Dean S.,Sercel, Anthony D.,Pearson, William H.,Mackie, Hugh,Randolph, John B.,Somers, Robert L.
, p. 2457 - 2461 (2007/10/03)
Pyrrolo-dC (1a, 6-methyl-3-(2-deoxy-β-D-ribofuranosyl)-3H-pyrrolo[2,3- d]pyrimidin-2-one) and its cyanoethyl phosphoramidite 2a were synthesized. The latter was incorporated into oligodeoxyribonucleotides by standard automated synthesis techniques, where
