38226-58-3Relevant academic research and scientific papers
The synthesis of chiral β-ketosulfoxides by enantioselective oxidation and their stereocontrolled reduction to β-hydroxysulfoxides
Cardellicchio, Cosimo,Omar, Omar Hassan,Naso, Francesco,Capozzi, Maria Annunziata M.,Capitelli, Francesco,Bertolasi, Valerio
, p. 223 - 229 (2006)
Various chiral non-racemic β-ketosulfoxides, a class of compounds frequently used in asymmetric synthesis, were prepared in good yields by tert-butyl hydroperoxide oxidation of the corresponding sulfides in the presence of a complex between titanium and (
Switchable Synthesis of Sulfoxides and α-Alkoxy-β-ketothioethers Regulated by Temperature in a Selectfluor-Methanol System
Wang, Jiateng,Liu, Mengxia,Zhang, Yue,Bi, Gehua,Zhao, Yi,Yang, Kai,Huang, Xin
, p. 14404 - 14419 (2021/11/01)
A switchable and benign protocol for chemoselective synthesis of sulfoxides and α-alkoxy-β-ketothioethers has been developed. It was determined that various thiophenols and alkenes/alkynes are compatible to realize the target compounds from a medium to a high yield by regulating the reaction temperature. In particular, methanol not only served as a solvent but also participated in the reaction process as a hydrogen donor. In this study, Selectfluor has been proved to be an efficient multifunctional reagent in the reaction system.
