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N-[2-(4-fluorophenyl)-1-methylethyl]ethylamine is an organic compound with the molecular formula C11H16FN. It is a derivative of ethylamine, featuring a fluorophenyl group attached to a secondary amine. This chemical is characterized by a 4-fluorophenyl ring, which imparts unique electronic properties due to the presence of a fluorine atom. The molecule's structure includes a methyl group attached to a 2-phenylethylamine backbone, which can influence its reactivity and interactions with other molecules. N-[2-(4-fluorophenyl)-1-methylethyl]ethylamine may be of interest in the fields of pharmaceuticals and materials science, where its specific structural features could be exploited for various applications, such as in the development of new drugs or as a building block in the synthesis of more complex molecules.

3823-30-1

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3823-30-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3823-30-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,2 and 3 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3823-30:
(6*3)+(5*8)+(4*2)+(3*3)+(2*3)+(1*0)=81
81 % 10 = 1
So 3823-30-1 is a valid CAS Registry Number.

3823-30-1Downstream Products

3823-30-1Relevant academic research and scientific papers

Photometric Characterization of the Reductive Amination Scope of the Imine Reductases from Streptomyces tsukubaensis and Streptomyces ipomoeae

Matzel, Philipp,Krautschick, Lukas,H?hne, Matthias

, p. 2022 - 2027 (2017)

Imine reductases (IREDs) have emerged as promising enzymes for the asymmetric synthesis of secondary and tertiary amines starting from carbonyl substrates. Screening the substrate specificity of the reductive amination reaction is usually performed by time-consuming GC analytics. We found two highly active IREDs in our enzyme collection, IR-20 from Streptomyces tsukubaensis and IR-Sip from Streptomyces ipomoeae, that allowed a comprehensive substrate screening with a photometric NADPH assay. We screened 39 carbonyl substrates combined with 17 amines as nucleophiles. Activity data from 663 combinations provided a clear picture about substrate specificity and capabilities in the reductive amination of these enzymes. Besides aliphatic aldehydes, the IREDs accepted various cyclic (C4–C8) and acyclic ketones, preferentially with methylamine. IR-Sip also accepted a range of primary and secondary amines as nucleophiles. In biocatalytic reactions, IR-Sip converted (R)-3-methylcyclohexanone with dimethylamine or pyrrolidine with high diastereoselectivity (>94–96 % de). The nucleophile acceptor spectrum depended on the carbonyl substrate employed. The conversion of well-accepted substrates could also be detected if crude lysates were employed as the enzyme source.

Method of treating nausea and vomiting with certain substituted-phenylalkylamino (and aminoacid) derivatives and other serotonin depleting agents

-

, (2008/06/13)

A method for the treatment of emesis in a mammal, which method comprises administering to said mammal an emesis inhibiting amount of a compound which depletes serotonin in the brain of mammals; among which are compounds having the formula: STR1 wherein, R is selected from hydrogen, loweralkyl, trifluoromethyl, carboxyl, or loweralkoxycarbonyl; R1 and R2 are hydrogen or loweralkyl; Z is trifluoromethyl or halogen; the optical isomers and pharmaceutically acceptable salts thereof; two of the preferred compounds of the invention are fenfluramine and norfenfluramine.