38230-41-0

Upstream product

• 10458-14-7 (2R,5S)-menthone 
• 109-94-4 formic acid ethyl ester 
• 110-45-2 isopentyl formate 
• 2516-99-6 3,3,3-Trifluoropropionic acid 

Downstream Products

• 51210-01-6 (3R)-3r-methyl-2ξ-hydroxymethyl-6t-isopropyl-cyclohexan-ξ-ol 
• 38230-42-1 2-n-Butylthiomethylen-p-menthan-3-on 
• 209865-17-8 (3R,6S)-2-formyl-2,3-dimethyl-6-isopropyl-cyclohexanone 
• 1185842-10-7 (3R,6S)-6-isopropyl-3-methyl-2-methylenecyclohexanol 
• 37842-16-3 1β-(butan-3-one)-menthone 
• 38230-43-2 2-n-Butylthiomethylen-p-menth-3-en 
• 209865-19-0 (E)-3-((1S,2S,3S,6R)-2-Ethynyl-2-hydroxy-3-isopropyl-1,6-dimethyl-cyclohexyl)-acrylic acid ethyl ester 
• 209865-18-9 (E)-3-((3S,6R)-3-Isopropyl-1,6-dimethyl-2-oxo-cyclohexyl)-acrylic acid ethyl ester 

Relevant academic research and scientific papers

Leptosperols A and B, Two Cinnamoylphloroglucinol-Sesquiterpenoid Hybrids from Leptospermum scoparium: Structural Elucidation and Biomimetic Synthesis

Leptosperols A and B (1 and 2), two cinnamoylphloroglucinol-sesquiterpenoid hybrids featuring unprecedented 1-benzyl-2-(2-phenylethyl) cyclodecane and 2-benzyl-3-phenylethyl decahydronaphthalene backbones, along with their biosynthetic precursor (3), were isolated from Leptospermum scoparium. Compounds 1 and 2 represent the first example of phloroglucinol derivatives biogenetically constructed by a De Mayo reaction. The biomimetic synthesis of leptosperol B (2) was achieved using the proposed biosynthetic pathway. In addition, compounds 1 and 2 showed significant anti-inflammatory effects in zebrafish acute inflammatory models.

Identification of a Strigoterpenoid with Dual Nrf2 and Nf-?°B Modulatory Activity

The sesquiterpene-coumarin ether samarcandone provided a suitable framework to replace the apocarotenoid A-C ring system of strigol (1), replicating, after linking to a butenolide moiety, the activity of the natural phytohormone on Nrf2 and also showing potent NF-kB inhibitory activity, overall modulating two critical pathways of inflammation and cancer.

Thieme chemistry journal awardees - Where are they now? Synthesis of (-)-cubebol by intramolecular cyclopropanation of a terminal epoxide

A synthesis of (-)-cubebol from l-menthone is described. The key step involves efficient (90%) and completely stereocontrolled intramolecular cyclopropanation of an unsaturated α-lithiated terminal epoxide. Georg Thieme Verlag Stuttgart.

New optically active pyrazoles: Syntheses and the structural characterization of menthopyrazole analogues

New chiral pyrazoles, (4R,7R)-4-methyl-7-isopropyl-3-phenyl- (3-phenylisomenthopyrazole; cis-1), (4R,7S)-4-methyl-7-isopropyl- (l-menthopyrazole; trans-2), (4R,7R)-4-isopropyl-7-methyl- (isocarvomenthopyrazole, cis-3) and (4R,7S)-4-isopropyl-7-methyl-4,5,6,7-tetrahydro-1H-indazole (carvomenthopyrazole, trans-3) were prepared. The diastereomeric pairs of these 1-3 were structurally characterized by NMR spectroscopy. The subtle differences of structures of 1-3 should induce the useful effects for a chiral auxiliary or a chiral catalyst.