37842-16-3Relevant academic research and scientific papers
Leptosperols A and B, Two Cinnamoylphloroglucinol-Sesquiterpenoid Hybrids from Leptospermum scoparium: Structural Elucidation and Biomimetic Synthesis
Chen, Jun-Zi,Cheng, Min-Jing,Gu, Ji-Hong,Hu, Li-Jun,Li, Chuang-Chuang,Li, Ni-Ping,Liu, Jun-Shan,Wang, Lei,Wang, Wen-Jing,Ye, Wen-Cai
, (2020)
Leptosperols A and B (1 and 2), two cinnamoylphloroglucinol-sesquiterpenoid hybrids featuring unprecedented 1-benzyl-2-(2-phenylethyl) cyclodecane and 2-benzyl-3-phenylethyl decahydronaphthalene backbones, along with their biosynthetic precursor (3), were isolated from Leptospermum scoparium. Compounds 1 and 2 represent the first example of phloroglucinol derivatives biogenetically constructed by a De Mayo reaction. The biomimetic synthesis of leptosperol B (2) was achieved using the proposed biosynthetic pathway. In addition, compounds 1 and 2 showed significant anti-inflammatory effects in zebrafish acute inflammatory models.
Autoxidation of 4-amorphen-11-ol and the biogenesis of nor- and seco-amorphane sesquiterpenes from Fabiana imbricata
Ngo, Koon-Sin,Brown, Geoffrey D.
, p. 15109 - 15126 (2007/10/03)
Photooxidation of 4-amorphen-11-ol (1), recently reported as one of the major sesquiterpene natural products from the medicinal plant Fabiana imbricata, results in three allylic hydroperoxides 6, 9 and 10, which are expected from the 'ene- type' reaction
