38270-12-1

Basic information

• Product Name: α-bromo-4-nitrochalcone
• Synonyms: α-bromo-4-nitrochalcone
• CAS NO: 38270-12-1
• Molecular Weight: 332.153
• Mol File: 38270-12-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: α-bromo-4-nitrochalcone(CAS DataBase Reference)
• NIST Chemistry Reference: α-bromo-4-nitrochalcone(38270-12-1)
• EPA Substance Registry System: α-bromo-4-nitrochalcone(38270-12-1)

Safety Data

• Hazardous Substances Data: 38270-12-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 38895-96-4 p-nitrochalcone dibromide 
• 127-08-2 potassium acetate 
• 24213-17-0 (trans)-2,3-dibromo-3-(4-nitrophenyl)-1-phenylpropan-1-one 
• 3201-60-3 α-bromobenzoylmethylene triphenylphosphorane 
• 555-16-8 4-nitrobenzaldehdye 
• 20913-05-7 (Benzoylmethylene)triphenylphosphorane 
• 6048-29-9 triphenylphenacylphosphonium bromide 
• 1222-98-6 4-nitrochalcone 

Downstream Products

• 24213-17-0 (2RS,3RS)-2,3-dibromo-3-(4-nitro-phenyl)-1-phenyl-propan-1-one 
• 174414-22-3 α-(2-amino-4-nitroanilino)-4-nitrochalcone 
• 109746-71-6 (2RS,3RS)-3-bromo-2-morpholino-3-(4-nitro-phenyl)-1-phenyl-propan-1-one 
• 109747-18-4 (2RS,3SR)-2-bromo-3-morpholino-3-(4-nitro-phenyl)-1-phenyl-propan-1-one 
• 1222-98-6 4-nitrochalcone 

Relevant articles and documents

Visible light-mediated metal-free double bond deuteration of substituted phenylalkenes

Various bromophenylalkenes were reductively photodebrominated by using 1,3-dimethyl-2-phenyl-1H-benzo-[d]imidazoline (DMBI) and 9,10-dicyanoanthracene. With deuterated DMBI analogs (the most effective was DMBI-d11), satisfactory to excellent isotopic yields were obtained. DMBI-d11 could also be regenerated from the reaction mixtures with a recovery rate of up to 50%. The combination of the photodebromination reaction with conventional methods for bromoalkene synthesis enables sequential monodeuteration of a double bond without the necessity of a metal catalyst. This journal is

Stereoselective synthesis of α-bromo-α,β-unsaturated ketones via wittig reaction

The synthesis of α-bromo benzoylmethylene triphenylphosphorane 2 is firstly reported and α-bromo ylide 2 has sufficient activity to undergo Wittig reaction, affording a novel method for the stereoselective synthesis of α-bromo-α,β-unsaturated ketones 5.