38281-49-1

Basic information

• Product Name: Benzofuran, 3-(bromomethyl)-
• CAS NO: 38281-49-1
• Molecular Formula: C9H7BrO
• Molecular Weight: 211.058
• Mol File: 38281-49-1.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: Benzofuran, 3-(bromomethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzofuran, 3-(bromomethyl)-(38281-49-1)
• EPA Substance Registry System: Benzofuran, 3-(bromomethyl)-(38281-49-1)

Safety Data

• Hazardous Substances Data: 38281-49-1(Hazardous Substances Data)

Upstream product

• 4687-23-4 3-hydroxymethylbenzofuran 
• 95-56-7 2-hydroxybromobenzene 
• 1878-62-2 2-(2-acetylphenoxy)acetic acid 
• 118-93-4 o-hydroxyacetophenone 
• 63815-27-0 2-(2'-acetylphenoxy)acetic acid ethyl ester 
• 52536-39-7 2-(prop-2-ynyloxy)benzenediazonium tetrafluoroborate 
• 4687-25-6 1-benzofuran-3-carbaldehyde 
• 28991-24-4 3-(2-bromophenoxy)acrylic acid ethyl ester 
• 194278-43-8 benzofuran-3-carboxylic acid ethyl ester 
• 21535-97-7 3-methyl-benzofuran 

Downstream Products

• 1240407-30-0 C₂₅H₂₅N₃O₂ 
• 1240407-34-4 1-(benzofuran-3-ylmethyl)-4-(4-iodophenyl)piperidin-4-ol 
• 1240407-37-7 8-(benzofuran-3-ylmethyl)-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 
• 1240407-38-8 8-(benzofuran-3-ylmethyl)-3-(2-fluoroethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 
• 1240407-33-3 1-(benzofuran-3-ylmethyl)-4-(4-bromophenyl)piperidin-4-ol 
• 64175-51-5 2-(3-benzofuranyl)acetic acid 
• 1028450-23-8 ethyl 6-[(1-benzofuran-3-ylmethyl)sulfanyl]cyclohex-1-ene-1-carboxylate 

Relevant articles and documents

Gold(I)-catalyzed endo-selective intramolecular α-alkenylation of β-yne-furans: Synthesis of seven-membered-ring-fused furans and dft calculations

Alkenylation of furans: An efficient gold-catalyzed endo-selective intramolecular α-alkenylation of β-alkyne-substituted furans has been developed to synthesize challenging seven-membered-ring-fused furans in good to excellent yields. Preliminary DFT calc

A carboxylate-assisted amination/unactivated C(sp2)-H arylation reactionviaa palladium/norbornene cooperative catalysis

This report describes a carboxylate-assisted palladium-catalysed Catellani reaction, which is compatible withortho-amination and unactivated C(sp2)-H arylation. This method was used to synthesize a series of 1-amino substituted dihydrophenanthridines, phenanthridines and 6H-benzo[c]chromenes. Based on kinetic isotope experiments, the kinetic curve proves that pivalic acid accelerates the reaction rate of unactivated C(sp2)-H activation, and thus this rate can keep up with the five membered aryl-norbornene-palladacycle (ANP) intermediate.

Mercapto-amide boronic acid derivative and application thereof as MBL (metal beta-lactamase) and/or SBL (serine beta-lactamase) inhibitor

The invention provides a compound of a formula (I) shown in the specification, or a conformational isomer, or an optical isomer or a pharmaceutically acceptable salt thereof. The compound of the formula (I) shown in the specification has excellent broad-spectrum inhibitory activity on MBL (metal beta-lactamase) and/or SBL (serine beta-lactamase), and can be used for preparing MBL and/or SBL inhibitors. Moreover, the compound disclosed by the invention has excellent antibacterial activity on multiple drug-resistant bacteria and is capable of reversing drug resistance of carbapenem drug-resistant bacteria, and the antibacterial effect of the compound is prior to those of positive control products such as L-captopril and tazobactam. The compound disclosed by the invention has very great potential in preparation of MBL/SBL dual inhibitors and medicines reversing drug resistance of carbapenem drug-resistance bacteria.